Fibromyalgia treatment guidelines from EULAR
Clinical Question
What are the preferred approaches to treating patients with fibromyalgia?Clinical Question
Bottom Line
Antidepressants, pramipexole (Mirapex and Sifrol), pregabalin (Lyrica), tramadol (Ultram), tropisetron (Navoban), and heated pool treatments have been shown to have short-term effectiveness in the treatment of fibromyalgia pain. (LOE = 1a-)Bottom Line
Reference
Carville SF, Arendt-Nielsen S, Bliddal H, et al. EULAR evidence-based recommendations for the management of fibromyalgia syndrome. Ann Rheum Dis 2008;7:536-541. [PMID:17644548]Reference
Funding
GovernmentFunding
Synopsis
These guidelines were developed by EULAR, a multidisciplinary task force of representatives from 11 European countries. To prepare this guideline, the group performed a comprehensive search and evaluation of the available medical literature, using a consensus system. Strong evidence was available only for drug therapy. Based on a good response in several small trials, the group recommends heated pool treatments with or without exercise (strength of evidence: B). Tramadol, antidepressants, tropisetron, pramipexole, and pregabalin are effective for reducing pain, and antidepressants can improve function (strength of evidence: A). There is only weak evidence supporting the use of tailored exercise programs, cognitive behavioral therapy, acetaminophen, or weak opioids. The group recommends against the use of corticosteroids or strong opioids. No research has evaluated the relative benefits of treatment, and most of the studies are short in duration, creating the possibility of a potent placebo effect.Synopsis
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Citation
Barry, Henry, et al., editors. "Fibromyalgia Treatment Guidelines From EULAR." EE+ POEM Archive, John Wiley & Sons, 2019. Evidence Central, evidence.unboundmedicine.com/evidence/view/infoPOEMs/426108/all/Fibromyalgia_treatment_guidelines_from_EULAR.
Fibromyalgia treatment guidelines from EULAR. In: Barry HH, Ebell MHM, Shaughnessy AFA, et al, eds. EE+ POEM Archive. John Wiley & Sons; 2019. https://evidence.unboundmedicine.com/evidence/view/infoPOEMs/426108/all/Fibromyalgia_treatment_guidelines_from_EULAR. Accessed April 1, 2023.
Fibromyalgia treatment guidelines from EULAR. (2019). In Barry, H., Ebell, M. H., Shaughnessy, A. F., & Slawson, D. C. (Eds.), EE+ POEM Archive. John Wiley & Sons. https://evidence.unboundmedicine.com/evidence/view/infoPOEMs/426108/all/Fibromyalgia_treatment_guidelines_from_EULAR
Fibromyalgia Treatment Guidelines From EULAR [Internet]. In: Barry HH, Ebell MHM, Shaughnessy AFA, Slawson DCD, editors. EE+ POEM Archive. John Wiley & Sons; 2019. [cited 2023 April 01]. Available from: https://evidence.unboundmedicine.com/evidence/view/infoPOEMs/426108/all/Fibromyalgia_treatment_guidelines_from_EULAR.
* Article titles in AMA citation format should be in sentence-case
TY - ELEC
T1 - Fibromyalgia treatment guidelines from EULAR
ID - 426108
ED - Barry,Henry,
ED - Ebell,Mark H,
ED - Shaughnessy,Allen F,
ED - Slawson,David C,
BT - EE+ POEM Archive
UR - https://evidence.unboundmedicine.com/evidence/view/infoPOEMs/426108/all/Fibromyalgia_treatment_guidelines_from_EULAR
PB - John Wiley & Sons
DB - Evidence Central
DP - Unbound Medicine
ER -