Active management in labour might possibly be effective for slightly reducing the caesarean section rates in low-risk pregnancies compared to routine care, but at the cost of increasing interventions.
A Cochrane review 1 included 7 studies with a total of 5390 nulliparous women. Active management includes routine amniotomy, strict rules for diagnosing slow progress, use of oxytocin and one-to-one care. The caesarean section (CS) rate was slightly lower in the active management group compared to routine care group (RR 0.88, 95% CI 0.77 to 1.01; 7 trials, n=5390). On excluding a study with a large number of post-randomisation exclusions, CS rates in the active management group were significantly lower than in the routine care group (RR 0.77 95% CI 0.63 to 0.94; 6 trials n=3475). More women in the active management group had labours lasting less than twelve hours, but there was wide variation in length of labour within and between trials. There were no differences between groups in use of analgesia, rates of assisted vaginal deliveries or maternal or neonatal complications. The majority of women (over 75%) in both groups were very satisfied with care in one trial.
Comment: The quality of evidence is downgraded by study quality (e.g. inadequate blinding), by inconsistency and indirectness (differences in studied interventions both in the intervention and the comparison groups).
1. Brown HC, Paranjothy S, Dowswell T, Thomas J. Package of care for active management in labour for reducing caesarean section rates in low-risk women. Cochrane Database Syst Rev. 2008;(4):CD004907 [Review content assessed as up-to-date: 27 June 2013].
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"Active Management in Labour for Reducing Caesarean Section Rates in Low-risk Women." Evidence-Based Medicine Guidelines, Duodecim Medical Publications Limited, 2019. Evidence Central, evidence.unboundmedicine.com/evidence/view/EBMG/456888/all/Active_management_in_labour_for_reducing_caesarean_section_rates_in_low_risk_women.
Active management in labour for reducing caesarean section rates in low-risk women. Evidence-Based Medicine Guidelines. Duodecim Medical Publications Limited; 2019. https://evidence.unboundmedicine.com/evidence/view/EBMG/456888/all/Active_management_in_labour_for_reducing_caesarean_section_rates_in_low_risk_women. Accessed January 28, 2021.
Active management in labour for reducing caesarean section rates in low-risk women. (2019). In Evidence-Based Medicine Guidelines. Duodecim Medical Publications Limited. Retrieved January 28, 2021, from https://evidence.unboundmedicine.com/evidence/view/EBMG/456888/all/Active_management_in_labour_for_reducing_caesarean_section_rates_in_low_risk_women
Active Management in Labour for Reducing Caesarean Section Rates in Low-risk Women [Internet]. In: Evidence-Based Medicine Guidelines. Duodecim Medical Publications Limited; 2019. [cited 2021 January 28]. Available from: https://evidence.unboundmedicine.com/evidence/view/EBMG/456888/all/Active_management_in_labour_for_reducing_caesarean_section_rates_in_low_risk_women.
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