A patient with drug addiction in primary care – Related resources

Cochrane reviews

  • Buprenorphine is more effective than clonidine or lofexidine and of similar effectiveness to methadone for the management of opioid withdrawal A.
  • Carbamazepine seems to have no effect for cocaine dependence, although there is no evidence from controlled trials C.
  • The use of antidepressants for cocaine abuse appears not to be beneficial B.
  • Dopamine antagonists appear not to be effective for cocaine dependence B.
  • There seems to be no significantly beneficial drug for the treatment of amphetamine dependence and withdrawal, although the evidence is insufficient. C.
  • Progressive withdrawal (over 10 weeks) appears to be more effective than abrupt withdrawal in the management of benzodiazepine mono-dependence B.
  • Contracts may have some potential in improving adherence to treatment, prevention and health promotion activities C.

Other evidence summaries

  • Family-couples therapy is superior to non-family modalities in the treatment of drug abuse
  • Educating young people may have only a very modest effect on drug using behaviour. Motivational interviewing and some family interventions may have some benefit B.


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TY - ELEC T1 - A patient with drug addiction in primary care – Related resources ID - 455190 BT - Evidence-Based Medicine Guidelines UR - https://evidence.unboundmedicine.com/evidence/view/EBMG/455190/all/A_patient_with_drug_addiction_in_primary_care___Related_resources PB - Duodecim Medical Publications Limited DB - Evidence Central DP - Unbound Medicine ER -