Acne – Related resources

Cochrane reviews

  • Minocycline appears to be effective for moderate to moderately-severe inflammatory acne vulgaris, but there is no evidence that it is better than any of the other commonly-used acne treatments, and concerns remain about its safety compared to other tetracyclines [Evidence Level: B].
  • There is not enough data to evaluate the effectiveness of spironolactone as treatment of acne [Evidence Level: C].

Clinical guidelines

  • Nast A, Dréno B, Bettoli V et al. European evidence-based (S3) guidelines for the treatment of acne. J Eur Acad Dermatol Venereol 2012;26 Suppl 1:1-29.  [PMID:22356611]

Other Internet resources


  • Simonart T, Dramaix M, De Maertelaer V. Efficacy of tetracyclines in the treatment of acne vulgaris: a review. Br J Dermatol 2008 Feb;158(2):208-16.  [PMID:17986300]
  • Sami NA, Attia AT, Badawi AM. Phototherapy in the treatment of acne vulgaris. J Drugs Dermatol 2008 Jul;7(7):627-32.  [PMID:18664153]
  • Krakowski AC, Stendardo S, Eichenfield LF. Practical considerations in acne treatment and the clinical impact of topical combination therapy. Pediatr Dermatol 2008 Jun;25 Suppl 1():1-14.  [PMID:18494684]

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