Alcoholics Anonymous and other 12-step programmes may have similar effect as other interventions for alcohol dependence. There is insufficient evidence on the effect of AA compared to no or minimal intervention.
A Cochrane review 1 included 8 trials involving a total of 3417 participants. Alcoholics Anonymous (AA) may help patients to accept treatment and keep patients in treatment more than alternative treatments, though the evidence for this is from one small study that combined AA with other interventions. Other studies reported similar retention rates regardless of treatment group (including Cognitive Behavioral Therapy and Motivational Enhancement Therapy). Three studies compared AA combined with other interventions against other treatments and found few differences in the amount of drinks and percentage of drinking days. Severity of addiction and drinking consequence did not seem to be differentially influenced by 12-step facilitation (TSF) approach vs comparison treatment interventions, and no conclusive differences in treatment drop out rates were reported. Included studies did not allow a conclusive assessment of the effect of 12-step approach in promoting complete abstinence.
Comment: The quality of evidence is downgraded by study quality (several limitations), by inconsistency (heterogeneity in interventions and outcomes).
1. Ferri M, Amato L, Davoli M. Alcoholics Anonymous and other 12-step programmes for alcohol dependence. Cochrane Database Syst Rev 2006 Jul 19;3:CD005032. [PMID:16856072]
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Alcoholics Anonymous and other 12-step programmes for alcohol dependence. Evidence-Based Medicine Guidelines. Duodecim Medical Publications Limited; 2019. https://evidence.unboundmedicine.com/evidence/view/EBMG/452204/all/Alcoholics_Anonymous_and_other_12_step_programmes_for_alcohol_dependence. Accessed September 28, 2020.
Alcoholics Anonymous and other 12-step programmes for alcohol dependence. (2019). In Evidence-Based Medicine Guidelines. Duodecim Medical Publications Limited. Retrieved September 28, 2020, from https://evidence.unboundmedicine.com/evidence/view/EBMG/452204/all/Alcoholics_Anonymous_and_other_12_step_programmes_for_alcohol_dependence
Alcoholics Anonymous and Other 12-step Programmes for Alcohol Dependence [Internet]. In: Evidence-Based Medicine Guidelines. Duodecim Medical Publications Limited; 2019. [cited 2020 September 28]. Available from: https://evidence.unboundmedicine.com/evidence/view/EBMG/452204/all/Alcoholics_Anonymous_and_other_12_step_programmes_for_alcohol_dependence.
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