Aerobic exercise appears to be safe and may be able to improve fitness and wellbeing for adults living with HIV/AIDS.
A Cochrane review 1 included 14 studies with a total of 718 subjects. Performing constant or interval aerobic exercise, or a combination of constant aerobic exercise and progressive resistive exercise for at least 20 minutes, at least three times per week for at least five weeks appears to be safe and may lead to significant improvements in selected outcomes of cardiopulmonary fitness (maximum oxygen consumption), body composition (leg muscle area, percent body fat), and psychological status (depression-dejection symptoms). These findings are limited to participants who continued to exercise and for whom there were adequate follow-up data.
Comment: The quality of evidence is downgraded by sparse data and study limitations (more than 20% loss to follow up).
1. O'Brien K, Nixon S, Tynan AM, Glazier R. Aerobic exercise interventions for adults living with HIV/AIDS. Cochrane Database Syst Rev 2010;(8):CD001796. [PMID:20687068]
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"Aerobic Exercise for People With HIV/AIDS." Evidence-Based Medicine Guidelines, Duodecim Medical Publications Limited, 2019. Evidence Central, evidence.unboundmedicine.com/evidence/view/EBMG/451924/all/Aerobic_exercise_for_people_with_HIV_AIDS.
Aerobic exercise for people with HIV/AIDS. Evidence-Based Medicine Guidelines. Duodecim Medical Publications Limited; 2019. https://evidence.unboundmedicine.com/evidence/view/EBMG/451924/all/Aerobic_exercise_for_people_with_HIV_AIDS. Accessed September 21, 2020.
Aerobic exercise for people with HIV/AIDS. (2019). In Evidence-Based Medicine Guidelines. Duodecim Medical Publications Limited. Retrieved September 21, 2020, from https://evidence.unboundmedicine.com/evidence/view/EBMG/451924/all/Aerobic_exercise_for_people_with_HIV_AIDS
Aerobic Exercise for People With HIV/AIDS [Internet]. In: Evidence-Based Medicine Guidelines. Duodecim Medical Publications Limited; 2019. [cited 2020 September 21]. Available from: https://evidence.unboundmedicine.com/evidence/view/EBMG/451924/all/Aerobic_exercise_for_people_with_HIV_AIDS.
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