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Allergen-specific immunotherapy – Related resources

Cochrane reviews

  • Immunotherapy is more effective than placebo for symptoms of asthma [Evidence Level: A].
  • Sublingual immunotherapy appears to be effective for ocular symptoms in patients with allergic rhinoconjunctivitis or allergic conjunctivitis compared to placebo [Evidence Level: B].


  • Alvarez-Cuesta E, Bousquet J, Canonica GW, Durham SR, Malling HJ, Valovirta E, EAACI, Immunotherapy Task Force. Standards for practical allergen-specific immunotherapy. Allergy 2006;61 Suppl 82():1-20.  [PMID:16930249]
  • Dahl R, Kapp A, Colombo G, de Monchy JG, Rak S, Emminger W, Rivas MF, Ribel M, Durham SR. Efficacy and safety of sublingual immunotherapy with grass allergen tablets for seasonal allergic rhinoconjunctivitis. J Allergy Clin Immunol 2006 Aug;118(2):434-40.  [PMID:16890769]
  • Passalacqua G, Durham S. Passalacqua G, Durham SR, Global Allergy and Asthma European Network. Allergic rhinitis and its impact on asthma update: allergen immunotherapy. J Allergy Clin Immunol 2007 Apr;119(4):881-91.  [PMID:17418661]
  • Rak S, Yang WH, Pedersen MR, Durham SR. Once-daily sublingual allergen-specific immunotherapy improves quality of life in patients with grass pollen-induced allergic rhinoconjunctivitis: a double-blind, randomised study. Qual Life Res 2007 Mar;16(2):191-201.  [PMID:17033900]
  • Savolainen J, Jacobsen L, Valovirta E. Sublingual immunotherapy in children modulates allergen-induced in vitro expression of cytokine mRNA in PBMC. Allergy 2006 Oct;61(10):1184-90.  [PMID:16942566]
  • EMEA Guidelins on the clinical development of products for specific immunotherapy for the treatment of allergic diseases. Doc .Rfe.CHMP/EWP/18504/2006, London 2008
  • Alvarez-Cuesta E, Bousquet J, Canonica GW, Durham SR, Malling HJ, Valovirta E, EAACI, Immunotherapy Task Force. Standards for practical allergen-specific immunotherapy. Allergy 2006;61 Suppl 82():1-20.  [PMID:16930249]
  • Canonica GW, Baena-Cagnani CE, Bousquet J, Bousquet PJ, Lockey RF, Malling HJ, Passalacqua G, Potter P, Valovirta E. Recommendations for standardization of clinical trials with Allergen Specific Immunotherapy for respiratory allergy. A statement of a World Allergy Organization (WAO) taskforce. Allergy 2007 Mar;62(3):317-24.  [PMID:17298350]
  • Halken S, Lau S, Valovirta E. New visions in specific immunotherapy in children: an iPAC summary and future trends. Pediatr Allergy Immunol 2008 Aug;19 Suppl 19():60-70.  [PMID:18665964]
  • van Wijk RG. When to initiate immunotherapy in children with allergic disease? Lessons from the paediatric studies. Curr Opin Allergy Clin Immunol 2008 Dec;8(6):565-70.  [PMID:18978473]
  • Jacobsen L, Niggemann B, Dreborg S, Ferdousi HA, Halken S, Høst A, Koivikko A, Norberg LA, Valovirta E, Wahn U, Möller C, (The PAT investigator group). Specific immunotherapy has long-term preventive effect of seasonal and perennial asthma: 10-year follow-up on the PAT study. Allergy 2007 Aug;62(8):943-8.  [PMID:17620073]
  • Berto P, Frati F, Incorvaia C. Economic studies of immunotherapy: a review. Curr Opin Allergy Clin Immunol 2008 Dec;8(6):585-9.  [PMID:18985948]

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"Allergen-specific Immunotherapy – Related Resources." Evidence-Based Medicine Guidelines, Duodecim Medical Publications Limited, 2019. Evidence Central, evidence.unboundmedicine.com/evidence/view/EBMG/450382/all/Allergen_specific_immunotherapy_–_Related_resources.
Allergen-specific immunotherapy – Related resources. Evidence-Based Medicine Guidelines. Duodecim Medical Publications Limited; 2019. https://evidence.unboundmedicine.com/evidence/view/EBMG/450382/all/Allergen_specific_immunotherapy_–_Related_resources. Accessed March 24, 2019.
Allergen-specific immunotherapy – Related resources. (2019). In Evidence-Based Medicine Guidelines. Available from https://evidence.unboundmedicine.com/evidence/view/EBMG/450382/all/Allergen_specific_immunotherapy_–_Related_resources
Allergen-specific Immunotherapy – Related Resources [Internet]. In: Evidence-Based Medicine Guidelines. Duodecim Medical Publications Limited; 2019. [cited 2019 March 24]. Available from: https://evidence.unboundmedicine.com/evidence/view/EBMG/450382/all/Allergen_specific_immunotherapy_–_Related_resources.
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TY - ELEC T1 - Allergen-specific immunotherapy – Related resources ID - 450382 BT - Evidence-Based Medicine Guidelines UR - https://evidence.unboundmedicine.com/evidence/view/EBMG/450382/all/Allergen_specific_immunotherapy_–_Related_resources PB - Duodecim Medical Publications Limited DB - Evidence Central DP - Unbound Medicine ER -