Abnormal menstrual bleeding – Related resources

Cochrane reviews

  • Danazol appears to be an effective treatment for heavy menstrual bleeding compared to other medical treatments, but its use is restricted by side effects and limited acceptability [Evidence Level: B].


  • Hurskainen R, Teperi J, Rissanen P, Aalto AM, Grenman S, Kivelä A, Kujansuu E, Vuorma S, Yliskoski M, Paavonen J. Quality of life and cost-effectiveness of levonorgestrel-releasing intrauterine system versus hysterectomy for treatment of menorrhagia: a randomised trial. Lancet 2001 Jan 27;357(9252):273-7.  [PMID:11214131]
  • Ferenczy A. Pathophysiology of endometrial bleeding. Maturitas 2003 May 30;45(1):1-14.  [PMID:12753939]
  • Hickey M, Balen A. Menstrual disorders in adolescence: investigation and management. Hum Reprod Update 2003 Sep-Oct;9(5):493-504.  [PMID:14640381]

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