Optical correction of refractive error for preventing and treating eye symptoms in computer users New

Abstract

Abstract Background

Computer users frequently complain about problems with seeing and functioning of the eyes. Asthenopia is a term generally used to describe symptoms related to (prolonged) use of the eyes like ocular fatigue, headache, pain or aching around the eyes, and burning and itchiness of the eyelids. The prevalence of asthenopia during or after work on a computer ranges from 46.3% to 68.5%. Uncorrected or under‐corrected refractive error can contribute to the development of asthenopia. A refractive error is an error in the focusing of light by the eye and can lead to reduced visual acuity. There are various possibilities for optical correction of refractive errors including eyeglasses, contact lenses and refractive surgery.

Objectives

To examine the evidence on the effectiveness, safety and applicability of optical correction of refractive error for reducing and preventing eye symptoms in computer users.

Search methods

We searched the Cochrane Central Register of Controlled Trials (CENTRAL); PubMed; Embase; Web of Science; and OSH update, all to 20 December 2017. Additionally, we searched trial registries and checked references of included studies.

Selection criteria

We included randomised controlled trials (RCTs) and quasi‐randomised trials of interventions evaluating optical correction for computer workers with refractive error for preventing or treating asthenopia and their effect on health related quality of life.

Data collection and analysis

Two authors independently assessed study eligibility and risk of bias, and extracted data. Where appropriate, we combined studies in a meta‐analysis.

Main results

We included eight studies with 381 participants. Three were parallel group RCTs, three were cross‐over RCTs and two were quasi‐randomised cross‐over trials. All studies evaluated eyeglasses, there were no studies that evaluated contact lenses or surgery. Seven studies evaluated computer glasses with at least one focal area for the distance of the computer screen with or without additional focal areas in presbyopic persons. Six studies compared computer glasses to other types of glasses; and one study compared them to an ergonomic workplace assessment. The eighth study compared optimal correction of refractive error with the actual spectacle correction in use. Two studies evaluated computer glasses in persons with asthenopia but for the others the glasses were offered to all workers regardless of symptoms. The risk of bias was unclear in five, high in two and low in one study. Asthenopia was measured as eyestrain or a summary score of symptoms but there were no studies on health‐related quality of life. Adverse events were measured as headache, nausea or dizziness. Median asthenopia scores at baseline were about 30% of the maximum possible score.

Progressive computer glasses versus monofocal glasses
 One study found no considerable difference in asthenopia between various progressive computer glasses and monofocal computer glasses after one‐year follow‐up (mean difference (MD) change scores 0.23, 95% confidence interval (CI) −5.0 to 5.4 on a 100 mm VAS scale, low quality evidence). For headache the results were in favour of progressive glasses.

Progressive computer glasses with an intermediate focus in the upper part of the glasses versus other glasses
 In two studies progressive computer glasses with intermediate focus led to a small decrease in asthenopia symptoms (SMD −0.49, 95% CI −0.75 to −0.23, low‐quality evidence) but not in headache score in the short‐term compared to general purpose progressive glasses. There were similar small decreases in dizziness. At medium term follow‐up, in one study the effect size was not statistically significant (SMD −0.64, 95% CI −1.40 to 0.12). The study did not assess adverse events.

Another study found no considerable difference in asthenopia between progressive computer glasses and monofocal computer glasses after one‐year follow‐up (MD change scores 1.44, 95% CI −6.95 to 9.83 on a 100 mm VAS scale, very low quality evidence). For headache the results were inconsistent.

Progressive computer glasses with far‐distance focus in the upper part of the glasses versus other glasses
 One study found no considerable difference in number of persons with asthenopia between progressive computer glasses with far‐distance focus and bifocal computer glasses after four weeks' follow‐up (OR 1.00, 95% CI 0.40 to 2.50, very low quality evidence). The number of persons with headache, nausea and dizziness was also not different between groups.

Another study found no considerable difference in asthenopia between progressive computer glasses with far‐distance focus and monofocal computer glasses after one‐year follow‐up (MD change scores −1.79, 95% CI −11.60 to 8.02 on a 100 mm VAS scale, very low quality evidence). The effects on headaches were inconsistent.

One study found no difference between progressive far‐distance focus computer glasses and trifocal glasses in effect on eyestrain severity (MD −0.50, 95% CI −1.07 to 0.07, very low quality evidence) or on eyestrain frequency (MD −0.75, 95% CI −1.61 to 0.11, very low quality evidence).

Progressive computer glasses versus ergonomic assessment with habitual (computer) glasses
 One study found that computer glasses optimised for individual needs reduced asthenopia sum score more than an ergonomic assessment and habitual (computer) glasses (MD −8.9, 95% CI −16.47 to −1.33, scale 0 to 140, very low quality evidence) but there was no effect on the frequency of eyestrain (OR 1.08, 95% CI 0.38 to 3.11, very low quality evidence).

We rated the quality of the evidence as low or very low due to risk of bias in the included studies, inconsistency in the results and imprecision.

Authors' conclusions

There is low to very low quality evidence that providing computer users with progressive computer glasses does not lead to a considerable decrease in problems with the eyes or headaches compared to other computer glasses. Progressive computer glasses might be slightly better than progressive glasses for daily use in the short term but not in the intermediate term and there is no data on long‐term follow‐up. The quality of the evidence is low or very low and therefore we are uncertain about this conclusion. Larger studies with several hundreds of participants are needed with proper randomisation, validated outcome measurement methods, and longer follow‐up of at least one year to improve the quality of the evidence.

Author(s)

Pauline Heus, Jos H Verbeek, Christina Tikka

Abstract

Plain language summary

Eyeglasses, contact lenses or eye surgery for preventing and treating eye symptoms in computer users

What is the aim of this review?

Computer users frequently complain about problems with their eyes, or headaches. Eyeglasses, contact lenses or surgery of the eye might help to decrease or prevent these symptoms. We examined the effects of these interventions on eye symptoms and quality of life.

Key messages

Computer glasses with specific types of lenses are no different to other types of computer glasses in terms of eye symptoms. Computer glasses might improve eye symptoms more than glasses designed for daily use in the short term but not at six months follow‐up and there is no evidence on long‐term follow‐up. Due to the very low quality of the evidence we are uncertain about this conclusion. There are no studies on contact lenses or eye surgery to decrease eye symptoms of computer users. Randomised studies are needed with hundreds of participants that better measure symptoms at one‐year follow‐up.

What was studied in the review?

We found eight studies with 381 participants. All studies evaluated eyeglasses. We found no studies evaluating contact lenses or surgery. Two studies looked at progressive computer glasses where the focus gradually changes from nearby to the distance of the computer screen but one did not report any data. Two studies examined progressive computer glasses in which the focus also extended a couple of meters beyond the computer screen. Five studies looked at progressive computer glasses whose focus gradually changed to far distance. One study examined if the spectacles that participants already had could be improved and whether that influenced their computer vision, but the study did not provide data. We judged the risk of bias to be unclear in four studies, high in two and low in another study.

What are the main results of the review?

Progressive computer glasses compared to other types of computer glasses
 One study found no difference in eye symptoms after one year between progressive computer glasses and computer glasses with only one focus.

Progressive computer glasses including middle distance focus in the upper part of the glasses compared to other types of glasses
 Two studies found a small difference in eye symptoms between progressive computer glasses including middle distance focus and progressive glasses for everyday use when the glasses had been used for a period of one week to one month. There was no difference in dizziness between the two kinds of glasses. Another study found no difference in eye symptoms after one year between progressive computer glasses and computer glasses with only one focus.

Progressive computer glasses including far‐away focus in the upper part of the glasses compared to other types of glasses
 Two different studies found no difference in eye symptoms after one month between computer glasses including a far‐away focus and bifocal or trifocal computer glasses. Another study found that after one year glasses with only one focus were just as good as computer glasses. One study compared progressive computer glasses to an assessment of the participant's computer work station and own (computer) glasses and found an improvement of asthenopia symptom‐score of about 40%.

How up‐to‐date is this review?

We searched for studies that had been published up to 20 December, 2017.

Author(s)

Pauline Heus, Jos H Verbeek, Christina Tikka

Reviewer's Conclusions

Authors' conclusions

Implications for practice

We found low to very low quality evidence that progressive computer glasses with or without focal areas for intermediate or long distance do not have a considerable effect on asthenopia or on headache compared to monofocal, bifocal, or trifocal glasses in persons with presbyopia who work with computers. However, progressive computer glasses also including intermediate or far‐distance focus might have a small beneficial effect in the short term compared to glasses for daily use but it is unclear if this can be sustained in the long term. A proportion of participants in all studies had complaints of asthenopia at the start of the study and it is unclear if the results are also applicable to a situation in which participants would have no asthenopia at the start of the intervention. There are no studies that have used computer glasses as a treatment for people that ask for help with their asthenopia.

There are insufficient data to draw conclusions on the effect of best possible optical correction.

Implications for research

There is a need for parallel group randomised studies that should better report their methods to enable judgement of the risk of bias. The risk of bias in studies can be decreased by blinding participants and providers, which can be achieved by providing the intervention eyeglasses in exactly the same frame with a code and not presenting them as superior. A uniform standardised outcome measure for asthenopia should be used, like the Computer Vision Questionnaire (del Mar Seguí 2015). Studies should be conducted in participants who clearly suffer from asthenopia or in participants who are clearly free from these complaints but at risk of developing them, such as older workers.

Cross‐over studies should at least properly randomise the order of the interventions and include habituation and wash‐out periods. The results should be reported as intra‐person differences with the standard deviations.

Given that most studies included in this review show no evidence of a considerable effect, the effect size is expected to be small. This means that studies are needed with at least several hundred participants to have enough power to detect small effect sizes.

Follow‐up of the participants to assess the outcomes should be at least a year because we would like to know if these optical corrections work in the long run.

New studies should clearly describe the construction of the eyeglasses that they provide for computer work and a rationale as to why this would decrease symptoms. Given that most workers have various tasks that require various focal areas, glasses with focal areas for nearby, computer distance and distance beyond the computer are probably the most useful.

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