Acute kidney injury
226 results
101 - 200Early initiation of RRT does not improve mortality in patients with sepsis and severe acute kidney injury
Timing of RRT in critically ill patients with acute kidney injury: verdict still out
HMG CoA reductase inhibitors (statins) for preventing acute kidney injury after surgical procedures requiring cardiac bypass
Testosterone does not increase major adverse cardiac events, but does increase risk of AFib, PE, acute kidney injury, and arrhythmia (TRAVERSE)
Rhabdomyolysis
Epidemic nephropathy
Furosemide to prevent or treat acute renal failure in adults
NSAIDs and risk of acute renal failure
Safe use of non-steroidal anti-inflammatory drugs (NSAIDs)
Ischaemic preconditioning for the reduction of renal ischaemia reperfusion injury
For patients with chronic kidney disease, prehydration prior to contrast-enhanced computed tomography is unnecessary
Clinical decision rule identifies AKI patients at low risk for hydronephrosis
Improved mortality with early initiation of RRT in critically ill patients
No mortality difference between early and delayed initiation of renal replacement therapy in critically ill patients with AKI
Early initiation of RRT in critically ill patients with AKI does not lower 90-day mortality
Interventions for protecting renal function in the perioperative period: Cochrane systematic review
Diabetic kidney disease (diabetic nephropathy)
Drug treatment for hypertension
Hydroxyethyl starch (HES) versus other fluid therapies: effects on kidney function
Intraoperative hypotension but no major adverse events with continuation of perioperative RASIs
ACE + ARB does not improve outcomes in pts with T2DM with impaired renal function (VA NEPHRON)
Bicarbonate- versus lactate-buffered solutions for acute continuous haemodiafiltration or haemofiltration: Cochrane systematic review
No benefit from revascularization for asymptomatic renal artery stenosis (ASTRAL)
Less renal replacement therapy with sodium bicarbonate infusion for patients with severe metabolic acidosis
Bicarbonate versus lactate solutions for acute peritoneal dialysis
Nephrotic syndrome
High versus low blood pressure targets for cardiac surgery while on cardiopulmonary bypass
Individualized perioperative BP management reduces post-op complications
Continuous renal replacement therapy (CRRT) for rhabdomyolysis: Cochrane systematic review
Aldosterone antagonists in addition to renin angiotensin system antagonists for preventing the progression of chronic kidney disease
Direct oral anticoagulants
Trimethoprim or trimethoprim-sulfamethoxazole and risk of hyperkalaemia among patients taking renin-angiotensin system blockers
No benefit with restrictive fluid strategy during perioperative period for major abdominal surgery
Buffered solutions versus 0.9% saline for resuscitation in critically ill adults and children
Effects of peri‐operative nonsteroidal anti‐inflammatory drugs on post‐operative kidney function for adults with normal kidney function
No clear advantage to balanced crystalloids over saline; though 1 study suggests a mortality benefit in patients with sepsis
Final report from SPRINT: lowering SBP below 120 mm Hg decreases major adverse cardiac events and all-cause mortality
Intensive treatment of elevated blood pressure in hospitalized patients associated with adverse events
Continuous infusion versus bolus injection of loop diuretics for acute heart failure
Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk
Non‐pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement therapy
Insulin and glucose‐lowering agents for treating people with diabetes and chronic kidney disease
Proteinuria
Hydroxyethyl starch (HES) versus other fluid therapies: effects on kidney function
SBP of 120 instead of 140 in nondiabetic, high-risk elderly leads to significant benefits and some harms (SPRINT)
TAVI versus open surgery for valve replacement in aortic stenosis
Fatigue
Cordyceps sinensis (a traditional Chinese medicine) for kidney transplant recipients
Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding
No differences in postoperative deaths or complications with stopping or continuing renin-angiotensin system inhibitors
Pharmacological interventions for preventing clotting of extracorporeal circuits during continuous renal replacement therapy
Amphotericin B deoxycholate versus liposomal amphotericin B: effects on kidney function: Cochrane systematic review
Tripterygium wilfordii Hook F (a traditional Chinese medicine) for primary nephrotic syndrome: Cochrane systematic review
Trimethoprim-sulfamethoxazole and risk of sudden death among patients taking renin-angiotensin system blockers
SBP of 120 instead of 140 in adults 75 years or older = significant benefits and some harms (SPRINT)
Interventions for idiopathic steroid‐resistant nephrotic syndrome in children
Increased mortality with K <3.5 or >4.5 in patients hospitalized with acute MI
Normothermic and hypothermic machine perfusion preservation versus static cold storage for deceased donor kidney transplantation
Increased blood creatinine concentration, eGFR and renal function tests
Rifaximin effective in decreasing post-TIPS hepatic encephalopathy in patients with cirrhosis
Treatment of chronic renal failure
Assessing a patient with an abnormal liver function test result
Prostaglandins for adult liver transplanted recipients
Three-day course of inhaled amikacin is effective in preventing ventilator-associated pneumonia
No difference with continuing vs stopping ACEIs or ARBs in adults who are undergoing major noncardiac surgery
Cytomegalovirus prophylaxis with antiviral agents for solid organ transplantation: Cochrane systematic review
Improved outcomes with complete revascularization in older adults with myocardial infarction (FIRE)
No benefit with balanced vs saline solution or slower vs faster rate for fluid resuscitation in ICU
Teicoplanin versus vancomycin for proven or suspected infection: Cochrane systematic review