Acute coronary syndrome
356 results
201 - 300CCTA reduces need for hospitalization in low to moderate risk patients in ED
Antithrombotic agents in primary health care
For atrial fibrillation with ACS or PCI, apixaban plus clopidogrel (without aspirin) is preferred (AUGUSTUS)
Concomitant use of clopidogrel and a PPI may increase risk of adverse CHD outcomes
Excess enoxaparin increases adverse outcomes in non-ST elevation ACS
Treatment of a near-drowning person
ACS risk similar with normal ECG performed during presence or absence of chest pain
Better medication adherence with intervention; clinical outcomes unchanged
Low HS-troponin I accurate in identifying patients at low risk of cardiac events
Adding ezetimibe to moderate-dose statin reduces nonfatal MI only (NNT = 58 for 6 years)
Small study finds recurrent spontaneous coronary artery dissection risk not associated with subsequent pregnancy
Platelet-function testing doesn't improve outcomes in elderly patients with stents after ACS
Cholesterol lowering cost-effective in high-risk elderly
Intensive lipid lowering reduces mortality following ACS
Two-hour protocol identifies patients at low risk of ACS
Restrictive transfusion strategy is best for hospitalized patients
High-sensitivity troponin I of less than 5 ng/L has negative predictive value of 99.9% for cardiac death at 1 year
Clinical decision rules for evaluating adults with chest pain in primary care are limited in number and utility — stay tuned
In ACS, 5 yrs of invasive tx decreases MI but not all cause mortality (FRISC-II)
Fewer major cardiac events with routine percutaneous coronary intervention in patients undergoing transcatheter aortic-valve implantation (NOTION-3)
Routine stress testing after negative biomarker testing seldom helpful
Invasive strategy best only for men and high-risk women with unstable angina/non-ST elevation MI
Low-dose rivaroxaban improves outcomes in patients with ACS (ATLAS)
Intravenous immunoglobulin for the treatment of Kawasaki disease
Accelerated protocol identifies chest pain patients at low risk for major cardiac events
Early treatment with ACE inhibitors in acute myocardial infarction
Echocardiography as an outpatient procedure
Intensive BP control modestly decreased the likelihood of a broad composite of CV events, but with methodologic limitations
Percutaneous coronary intervention does not improve outcomes for patients with ischemic heart disease and LVEF of less than 35%
For atrial fibrillation with stable coronary artery disease, edoxaban alone prevents more bad outcomes than edoxaban plus an antiplatelet agent
Exercise stress test
Nitrates for acute heart failure syndromes
Clopidogrel plus aspirin vs aspirin alone for preventing cardiovascular events
Similar outcomes after PCI in hospitals with or without on-site cardiac surgery (CPORT-E)
Drug treatment for hypertension
Overuse alert: treat-to-target LDL strategy of statin dosing is noninferior to high-intensity dosing
Coronary sinus-reducing device improves symptoms for patients with refractory angina
Clopidogrel monotherapy more effective than aspirin to prevent coronary events after PCI with drug-eluting stents (HOST-EXAM)
Early invasive strategy does not reduce mortality for moderate to severe ischemic heart disease after 5.8 years (ISCHEMIA-EXTEND)
In low-risk patients with ACS, noninvasive testing adds little to clinical evaluation
Ticagrelor (Brilinta) is no better than aspirin—and may be worse—for adults after CABG
Adults with nonobstructive vulnerable coronary plaques have fewer major cardiac events with PCI than with optimal medical therapy
B vitamins, fish oil do not prevent CV events
Omega‐3 fatty acids for the primary and secondary prevention of cardiovascular disease
Adding CCTA to chest pain assessment reduces likelihood of nonfatal MI (SCOT-HEART)
Prophylactic lidocaine for myocardial infarction
Traditional approach to pretest probability of heart disease overestimates risk
Dyspnoea
Pioglitazone does not increase cardiovascular events (PROactive)
Flu vaccine reduces risk of adverse CV events in high-risk patients
Long-term outcomes better with CABG than PCI in pts with complex CAD (SYNTAX)
Faster discharge but more downstream testing with use of CCTA in ED
High-sensitivity troponin safely reduces admissions and duration of stay in the emergency department
Corticosteroids for the treatment of Kawasaki disease in children
Little if any benefit to early invasive strategy for stable angina and at least moderate reversible ischemia (ISCHEMIA trial)
Systemic lupus erythematosus (SLE)
Niacin not effective in CAD with low HDL cholesterol (AIM-HIGH)
Less is more when it comes to blood transfusions
In patients with vascular disease, treating sleep apnea does not reduce the risk of cardiovascular events
Lipid lowering is beneficial for secondary prevention but not primary prevention in patients 75 years and older
Similar number of cardiovascular events and reduced bleeding with abbreviated dual antiplatelet therapy after PCI
Antiplatelet therapy for prevention of death, myocardial infarction, and stroke
6-month clopidogrel better than 24 after stent placement (PRODIGY)
Clarithromycin associated with cardiovascular events
Interpretation of adult ECG
COVID-19 and other coronavirus infections
Dialysate temperature reduction for intradialytic hypotension for people with chronic kidney disease requiring haemodialysis
Mortality rate in patients with recent ACS and endoscopy is similar to that in patients with ACS and no endoscopy
Tumours of haematopoietic and lymphoid tissues: general information
Increased readmissions and adverse events with intensification of antihypertensive regimen on hospital discharge
Taking furosemide on day of surgery does not increase intraop hypotension
No reduction in postdischarge medication errors after pharmacist-led intervention
Adenosine-diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2 diabetes mellitus: Cochrane systematic review
Antiplatelet agents for chronic kidney disease
Clopidogrel + ASA no better than ASA alone for high-risk patients
Glycoprotein IIb-IIIa inhibitors for acute ischaemic stroke: Cochrane systematic review
Hyperbaric oxygen therapy (HBOT)
Small reduction in CV outcome after ischemic stroke with lower LDL target, but also harms; no change in all-cause mortality
Interpreting BNP in patients with a history of HF
Promoting patient utilisation of cardiac rehabilitation
Statin therapy decreases cardiac events