Angiotensin receptor blockers for heart failure
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1 - 88Angiotensin receptor blockers for heart failure
Angiotensin receptor blockers for heart failure
Nurse‐led titration of angiotensin converting enzyme inhibitors, beta‐adrenergic blocking agents, and angiotensin receptor blockers for people with heart failure with reduced ejection fraction
Chronic heart failure
LCZ696 (sacubitril/valsartan) for patients with heart failure
Heart failure nurse-led titration of heart failure medicines
Angiotensin receptor blockers or angiotensin converting enzyme inhibitors in the prevention of atrial fibrillation
SGLT2 inhibitors optimal drug class for heart failure with preserved and mildly reduced ejection fraction
Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of diabetic kidney disease
Beta‐blockers and inhibitors of the renin‐angiotensin aldosterone system for chronic heart failure with preserved ejection fraction
ACE inhibitor preferred over ARB in patients with ischemic heart disease
ARB treatment of high CV risk patients
Valsartan/sacubitril reduces mortality more than enalapril 10 mg twice daily in patients with heart failure (PARADIGM-HF)
Drugs for chronic heart failure with preserved ejection fraction
Diagnosing and managing acute heart failure Guidelines: NICE
First‐line diuretics versus other classes of antihypertensive drugs for hypertension
Angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers for preserving residual kidney function in peritoneal dialysis patients
Hypertrophic cardiomyopathy
ACE inhibitors and angiotensin II receptor blockers for diabetics with microalbuminuria
Guideline for the management of heart failure: early prevention for patients at risk, quadruple therapy for those with symptoms
Calcium channel blockers versus other classes of drugs for hypertension
ACE inhibitors decrease cardio events in patients with diabetes, ARBs don't
First-line drugs inhibiting the renin angiotensin system versus other first-line antihypertensive drug classes for hypertension: Cochrane systematic review
Eplerenone reduces mortality in NYHA II heart failure
For patients with AMI and preserved ejection fraction, long-term beta-blockers do not improve outcomes (REDUCE-AMI)
Drug treatment for hypertension
Renin inhibitors versus angiotensin receptor blockers for primary hypertension
Dilated cardiomyopathy
Choice of prophylactic medication for atrial fibrillation - Image
No improved patient-oriented outcomes with sacubitril/valsartan in adults with heart failure and preserved EF (PARALLAX)
Finerenone decreases hospitalization for heart failure in patients with type 2 diabetes and chronic kidney disease (NNT = 189/year)
Hypertension in elderly patients
Acute coronary syndrome
Digitalis for treatment of heart failure in patients in sinus rhythm
First-line renin angiotensin system inhibitors versus other drug classes for hypertension
Beta-blockers in patients without heart failure after myocardial infarction
Bedtime instead of morning ingestion of hypertension meds = significantly more reduction in cardiovascular disease risk
Pharmacological interventions for heart failure in people with chronic kidney disease
Compliance with heart failure performance measures not associated with improved outcomes
No differences in postoperative deaths or complications with stopping or continuing renin-angiotensin system inhibitors
Antihypertensive agents for preventing diabetic kidney disease
ACE inhibitors and angiotensin receptor blockers for progression of non-diabetic renal disease
Finerenone reduces composite cardiovascular outcome and risk of decreased eGFR, but increases risk of hyperkalemia
Aldosterone receptor antagonists spironolactone and eplerenone for congestive heart failure
JNC 8 report on prevention/evaluation/treatment of hypertension
Different antihypertensive agents as first line therapies
Acute kidney injury
Perioperative angiotensin‐converting enzyme inhibitors or angiotensin II type 1 receptor blockers for preventing mortality and morbidity in adults
Angiotensin‐converting enzyme inhibitors and angiotensin receptor blockers for adults with early (stage 1 to 3) non‐diabetic chronic kidney disease
Chronic diseases and pregnancy
Dapagliflozin reduces mortality and renal replacement in patients with chronic kidney disease
Rhythm control no better than rate control in AF + CHF
Choice of antihypertensive drug in the diabetic patient from prognostic point of view
Effect of antihypertensive drugs on mortality, morbidity and blood pressure in blacks: Cochrane systematic review
Irbesartan slows aortic dilation, but doesn't reduce the rate of surgery in those with Marfan syndrome (AIMS)
Antihypertensive therapy beneficial for patients with BP < 140/90 and history of CVD
Ventricular tachycardia
BP target of 120 no better than 140 in T2DM (ACCORD)
Higher blood pressure targets for hypertension in older adults
Secondary hypertension
Leg oedema
SBP of 120 instead of 140 in nondiabetic, high-risk elderly leads to significant benefits and some harms (SPRINT)
Natriuretic peptide‐guided treatment for the prevention of cardiovascular events in patients without heart failure
The most common types of acquired adult valvular heart disease and associated murmurs
Treatment of chronic renal failure
Use of medication during pregnancy