PSA for screening of prostate cancer
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PSA test in prostate cancer screening - PSA for screening of prostate cancer
PSA screening for prostate cancer not recommended (USPSTF)- Prostate cancer
- PSA screening does not reduce mortality from prostate CA (PLCO)
- PSA screening does not decrease mortality
- Low-intensity PSA-based screening does not reduce mortality, but leads to overdiagnosis and potential harm
- USPSTF 2018 recommends counseling 55 to 69-year-old men on benefits and harms of prostate cancer screening (C recommendation)
- USPSTF: No PSA screening in men 75 years and older
- Population screening for cancer
- PSA screening has marginal effect on mortality in European study (ERSPC)
- PSA plus MRI-guided biopsy reduces the detection of clinically insignificant prostate cancers more than systematic biopsy
- Benign prostatic hyperplasia
- Prostate cancer screening increases harm risk without decreasing mortality
- Prediction model can decrease prostate biopsies in men with abnormal PSA
- Modelling study shows less-intense screening is okay for men with low baseline PSA levels
- Impact of PSA screening on quality of life
Screening for prostate cancer- For men with PSA > 3.0, limiting biopsy to lesions seen on MRI appears to be safe
- Prostate cancer screening: no mortality benefit after 13 years of follow-up (PLCO)
- 5‐alpha‐reductase inhibitors for prostate cancer prevention
- Prostatectomy reduces mortality compared with no surveillance in men with T2 cancer who presented with symptoms
- The full truth about prostate cancer screening is suppressed again (ERSPC)
- Prostate cancer screening: no mortality benefit after 15 years of follow-up (PLCO)
- Five-alpha-reductase inhibitors for prostate cancer prevention
- Need to screen 1055 and treat 37 to prevent one prostate CA death over 11 years (ERSPC)
- Lycopene for the prevention of prostate cancer
- Ask-tell-ask approach to discussing prostate cancer screening
- Observation = radical prostatectomy for most pts with localized prostate cancer (PIVOT)
- Radical prostatectomy versus watchful waiting for newly diagnosed prostate cancer
- Haematuria
- Radical prostatectomy versus deferred treatment for localised prostate cancer