Warfarin therapy
91 results
1 - 91Don't add aspirin to warfarin therapy except with mechanical heart valve
Discontinuing warfarin therapy indefinitely after GI bleeding assoc with worse outcomes
Continued warfarin better than bridging therapy for pacemaker or defibrillator surgery (BRUISE CONTROL)
Warfarin superior to antiplatelet treatment for A Fib
Warfarin can safely be held for the short term
Benefits to resuming warfarin in patients with atrial fibrillation after intracranial bleeds
Tinzaparin no better than warfarin in preventing recurrent VTE in adults with cancer
Continuing warfarin for 18 months after unprovoked PE reduces risk of recurrent VTE
Warfarin: damned if you do, damned if you don't
Bleeding risk with warfarin high among elderly, especially older than 80
Many patients using warfarin also take aspirin
Clinically significant bleeding occurs in 3.8% per year of pts aged 65+ years using warfarin
6 months of warfarin after aortic valve replacement reduces risk of CV death
Dual therapy with dabigatran and clopidogrel preferred after PCI for patients with AF (RE-DUAL PCI)
Closure of PFO similar to medical therapy for cryptogenic stroke or TIA
More harm than good with bridge therapy in low-risk VTE patients
NOACs preferred over warfarin for nonvalvular atrial fibrillation in patients also taking low-dose aspirin
Dabigatran reduces risk of stroke and embolism in patients with AF
Percutaneous left atrial appendage closure reduces AF stroke risk
Rivaroxaban + clopidogrel causes somewhat less bleeding than triple therapy in patients with AF undergoing PCI
Coumadin + aspirin no better than aspirin alone for PAD
Extended anticoagulation may be helpul for patients with unprovoked VTE or PE
Genetic information does not add benefit to a clinical algorithm for warfarin management
ACC/AHA guidelines for atrial fibrillation
Genotype-guided perioperative warfarin dosing may not be superior to algorithm-guided dosing
Use of antithrombotic medications increases risk of hematuria-related complications
Taking vitamin K antagonists after ICH: the good, the bad, and the ugly (CHIRONE)
Clopidogrel + ASA for afib: fewer strokes, more hemorrhages (ACTIVE)
Joint injection okay in anticoagulated patients
Rivaroxaban similar to warfarin for patients with NVAF
Dabigatran cost-effective for AF prophylaxis in some patients, not others
VTE recurrence higher in men
Slightly lower risk of major bleeds with apixaban (NNT = 83); no difference in efficacy
Oral rivaroxaban as effective as standard therapy for treatment of acute PE
Rivaroxaban effective for acute DVT (EINSTEIN)
Dabigatran associated with increased risk of coronary events
Bridging anticoagulation in patients with AF associated with more CVEs and bleeding
Anticoagulation reversal with vitamin K doesn't reduce bleeding
ACCP 2016: updated guidelines for VTE
Updated American College of Chest Physicians guideline on antithrombotic therapy for venous thromboembolism
2023 American Geriatric Society update on potentially inappropriate medication use in the elderly (Beers List)
ACCP guidelines for antithrombotics in atrial fibrillation
Aspirin is no different than other anticoagulants for VTE prevention after joint replacement surgery
For atrial fibrillation with ACS or PCI, apixaban plus clopidogrel (without aspirin) is preferred (AUGUSTUS)
D-dimer can identify high-risk group for extended anticoagulation (PROLONG)
The DOAC score determines bleeding risk for patients with atrial fibrillation who take a direct-acting oral anticoagulant