Rare diseases
33 results
1 - 33
Limited management options for bed bugs- Vaccine safe and effective for prevention of EV71 disease (NNT = 50 over 1 year)
- HPV-16 vaccine may be effective for vulvar intraepithelial neoplasia
- No benefit to screening with CT angiography for asymptomatic CAD in adults with diabetes
- Low-volume sulfate prep is effective and well tolerated
- Semaglutide is associated with an increased risk of optic neuropathy
- Benign thyroid nodules rarely progress to malignancy (0.3% in 5 years)
- USPSTF 2019 recommends offering PrEP to patients at high risk of HIV acquisition (A recommendation)
- In patients with T2DM and nephropathy, canagliflozin reduces likelihood of end-stage kidney disease and adverse CV outcomes
- Finerenone decreases hospitalization for heart failure in patients with type 2 diabetes and chronic kidney disease (NNT = 189/year)
- Sotrovimab reduces the likelihood of hospitalization in at-risk outpatients with mild to moderate COVID-19 (NNT = 16)
- Bamlanivimab plus etesevimab reduces the likelihood of hospitalization or death in high-risk outpatients with COVID-19 (NNT = 20)
- 2023 American Geriatric Society update on potentially inappropriate medication use in the elderly (Beers List)
- Most endocarditis prophylaxis no longer necessary: NICE guideline
- Similar outcomes after PCI in hospitals with or without on-site cardiac surgery (CPORT-E)
- Guidelines not helpful in patients with multiple conditions
- Tirzepatide helps obese adults without diabetes lose 15% to 21% of their body weight over 72 weeks
- MRSA common in abscessed skin infections
- Multiple steroid injections into arthritic joints do not improve outcomes more than other injections
- Influenza vaccine shortly after myocardial infarction reduces 1-year mortality (NNT = 50)
- Inpatient treatment = outpatient treatment for anorexia
- Clomiphene better than metformin for PCOS infertility
- Unexplained complaints commonly remain unexplained a year later
- ATS guideline on evaluating wheezing infants: no evidence, many recommendations
- CCTA reduces need for hospitalization in low to moderate risk patients in ED
- Glyburide not beneficial for women with mild gestational diabetes
- AAN Guideline on managing patients with restless leg syndrome
- Diagnostic certainty for type of stroke requires neuroimaging
- Patent foramen ovale closure in cryptogenic stroke reduces recurrence rate compared with antiplatelet agents
- Nifedipine plus sildenafil reduces preterm birth more than nifedipine alone
- Quadrivalent flu vaccine is safe and effective, but may not be better than trivalent
- Pergolide, cabergoline increase risk of heart valve damage