Prevention of atrial fibrillation
121 results
1 - 100Low-dose edoxaban effective for stroke prevention for elderly patients with atrial fibrillation
Screening high-risk patients for atrial fibrillation with implantable loop recorder does not prevent stroke or systemic emboli (LOOP)
For atrial fibrillation with stable coronary artery disease, edoxaban alone prevents more bad outcomes than edoxaban plus an antiplatelet agent
For patients with subclinical intermittent atrial fibrillation, apixaban prevents 1 stroke and causes 1 major bleed per 250 persons (ARTESIA)
Atrial fibrillation recurrence higher with episodic treatment with amiodarone
Cryoablation preferred as initial therapy for paroxysmal atrial fibrillation (EARLY-AF)
ARBs & ACE inhibitors prevent A fib
Rhythm control is associated with a lower risk of cognitive decline than rate control in adults with atrial fibrillation
USPSTF 2022 concludes evidence is insufficient to recommend screening for asymptomatic atrial fibrillation (I statement)
Older patients with atrial fibrillation treated with DOACs have fewer strokes and systemic emboli than those treated with vitamin K antagonists
The DOAC score determines bleeding risk for patients with atrial fibrillation who take a direct-acting oral anticoagulant
Dronedarone reduces hospitalization but not mortality in atrial fibrillation
Percutaneous left atrial appendage closure reduces AF stroke risk
For device-detected atrial fibrillation, anticoagulation decreases stroke risk (NNT = 100), increases major bleeding (NNTH = 62)
Warfarin prevents more strokes than clopidorel+ASA in a fib (ACTIVE)
Warfarin > aspirin in preventing strokes in pts older than 75 with A fib (BAFTA)
Dronedarone prevents AF recurrence but effect on symptoms unknown
The prognosis is similar for adults with symptomatic versus asymptomatic atrial fibrillation
Adults with atrial fibrillation who survive ICH and resume DOACs have fewer strokes but more recurrent ICH (PRESTIGE-AF)
Lenient = strict rate control in prevention of adverse outcomes in AF
NOACs preferred over warfarin for nonvalvular atrial fibrillation in patients also taking low-dose aspirin
Dabigatran reduces risk of stroke and embolism in patients with AF
Catheter ablation of AF prevents recurrence but has minimal impact on QOL
Colchicine prevents postpericardiotomy syndrome following cardiac surgery
Apixaban reduces stroke and embolism more than aspirin in A fib
Benefits to resuming warfarin in patients with atrial fibrillation after intracranial bleeds
ABC (Age, Biomarkers, Clinical history) score predicts stroke risk in atrial fibrillation
No worsening of post-op atrial arrhythmias with relaxed potassium supplementation following coronary artery bypass grafting (TIGHT K)
Fewer major bleeds with edoxaban than with warfarin, but treatment benefit unclear (ENGAGE-AF)
Greater risk of serious bleeding with diltiazem vs metoprolol in adults with atrial fibrillation using apixaban or rivaroxaban
Warfarin superior to antiplatelet treatment for A Fib
Screening for atrial fibrillation in primary care is not effective (VITAL-AF)
USPSTF 2018: insufficient evidence to recommend screening for AFib with ECG (I statement)
Benefits/harms of novel oral anticoagulants similar in general population and the elderly
Early anticoagulation after ischemic stroke is a safe strategy (ELAN)
Beta-blockers don't decrease mortality in patients with AF + CHF
Rivaroxaban + clopidogrel causes somewhat less bleeding than triple therapy in patients with AF undergoing PCI
Prescription omega-3 fatty acids do not reduce risk of recurrent A fib
In adults with atrial fibrillation and acute ischemic strokes, early (within 4 days) and delayed (7-10 days) initiation of DOACs have similar outcomes (OPTIMAS)
Rivaroxaban similar to warfarin for patients with NVAF
AHA guideline for secondary stroke prevention
Warfarin provides greater net benefit than rivaroxaban for patients with atrial fibrillation and rheumatic heart disease
New anticoagulants vs warfarin in A fib: no clear winner
Increased GI bleeding after switch from warfarin to dabigatran
Dual therapy with dabigatran and clopidogrel preferred after PCI for patients with AF (RE-DUAL PCI)
No reduction in stroke recurrence with apixaban vs aspirin in patients with cryptogenic stroke and atrial cardiopathy (ARCADIA)
Bleeding risk with warfarin high among elderly, especially older than 80
Radiofrequency ablation an option for healthy younger patients with paroxysmal AF