Chronic obstructive pulmonary disease (COPD)
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Gabapentinoids are associated with severe exacerbations of chronic obstructive pulmonary disease- Pulmonary rehabilitation after hospitalization for chronic obstructive pulmonary disease improves mortality
- Guidelines for COPD (ACP)
- Summary of GOLD guideline for COPD
- Guidelines for the management of COPD
- Corticosteroids benefit patients with moderate to severe COPD
- Inhaled budesonide for COPD not associated with pneumonia
- Bisoprolol does not reduce exacerbations in adults with chronic obstructive pulmonary disease (BICS)
- Oral = IV prednisolone for COPD exacerbation
- Canadian Thoracic Society guidelines for pharmacotherapy of stable chronic obstructive pulmonary disease
- Self-management teaching not helpful for COPD
- Prevalence of pulmonary embolism is 5.9% in patients with COPD who are hospitalized with acute respiratory symptoms
- Antibiotic and corticosteroid treatment effective for acute exacerbations of COPD
- Anticholinergics of greater benefit in COPD treatment
- Physician assessment of COPD doesn't match spirometry results
- Inhaled steroids only decrease COPD exacerbations slightly
- USPSTF: D recommendation against screening for COPD in asymptomatic adults
- Inhaled corticosteroids increase pneumonia risk in stable COPD
- Corticosteroids, selective use of antibiotics and NPPV for COPD exacerbations
- Tiotropium mist associated with mortality in COPD treatment
- Azithromycin of questionable benefit given daily for COPD
- Fluticasone plus vilanterol an option for COPD
- Long-term erythromycin decreases COPD exacerbations
- Simple risk score predicts severity of COPD exacerbations
- USPSTF 2022: Recommendation against screening for chronic obstructive pulmonary disease (D recommendation)
- Supplemental oxygen ineffective for COPD with moderate hypoxemia
- Inhaled steroids for COPD associated with increased risk of pneumonia
- Tiotropium not associated with increase cardiovascular risk in patients with COPD
- Long-acting bronchodilators similarly safe in COPD patients
- Procalcitonin test can reduce antibiotic use in COPD
- American Thoracic Society home oxygen guideline for patients with COPD or interstitial lung disease
- For mild to severe COPD exacerbations, antibiotics and steroids remain the mainstay of treatment
- Sputum purulence and CRP predict poor prognosis with COPD exacerbation
- Improved outcomes with azithromycin vs beta-lactams for acute exacerbations of chronic obstructive pulmonary disease
- In high-risk patients with chronic obstructive pulmonary disease, dupilumab slightly reduces moderate exacerbation (BOREAS)
- Inhaled anticholinergics associated with increased risk of CVD in COPD
- Fluticasone + salmeterol may reduce mortality but also increase pneumonia in COPD
- Salmeterol + fluticasone better than tiotropium in COPD (INSPIRE)
- COPD -- combo therapy improves symptoms but doesn't decrease exacerbations
- 5-day steroid treatment effective for acute COPD exacerbation
- Better outcomes with noninvasive ventilation for hospitalized COPD patients
- No change in duration of mechanical ventilation with acetazolamide for COPD patients with metabolic alkalosis
- Short-course antibiotics effective for acute exacerbation of COPD
- Self-management training, routine monitoring not effective for COPD
- DECAF score provides accurate prognosis for patients with acute exacerbation of COPD
- Mepolizumab provides a small reduction in the exacerbations of moderate to severe eosinophilic COPD
- Beta-blockers associated with improved morbidity/mortality in COPD patients
- Amox-clavulanate during COPD exacerbations decreases Sx and delays subsequent exacerbations
- Tiotropium via Soft Mist Inhaler increases all-cause mortality in COPD
- Reduced readmissions with home NIV plus oxygen for COPD exacerbation with persistent hypercapnia
- Uncertain benefit of home noninvasive positive pressure ventilation for adults with chronic obstructive pulmonary disease
- Helium-oxygen improves exercise tolerance in pts with COPD
- 3-in-1 inhaler for chronic obstructive pulmonary disease may provide better outcomes than multiple individual inhalers (SKOPOS-MAZI)
- Low-dose theophylline is minimally helpful, if at all, in preventing COPD exacerbations
- Early outpatient follow-up linked with fewer readmissions for COPD patients
- Three-month spirometry does not improve health outcomes for patients with asthma and/or COPD
- C-reactive protein helps reduce antibiotic prescribing for COPD exacerbations
- O2 not helpful in overall QOL in COPD with exertional hypoxia
- Risk of serious pneumonia in COPD patients using inhaled corticosteroids
- High-efficiency air cleaners decrease exacerbations and the use of rescue medication in former smokers with COPD
- One year of once-daily doxycycline does not reduce exacerbation frequency in adults with moderate to severe COPD
- Population-based case-finding intervention to identify undiagnosed COPD and asthma has minimal benefits
- Mepolizumab provides only a small reduction in moderate exacerbations when added to triple inhaler therapy for eosinophilic COPD (MATINEE)
- Low-dose oral = high-dose IV steroids for initial treatment of acute COPD exacerbation
- Steroid inhalers increase fracture risk in COPD