Acute kidney injury
102 results
1 - 100Prediction tool for chronic kidney disease following acute kidney injury
No difference in acute kidney injury but more delirium with cefepime instead of piperacillin-tazobactam (ACORN)
Timing of RRT in critically ill patients with acute kidney injury: verdict still out
Early initiation of RRT does not improve mortality in patients with sepsis and severe acute kidney injury
Decreased risk of postoperative acute kidney injury with continuous amino acid infusion during and after cardiac surgery
No mortality benefit, increased risk of acute kidney injury with addition of beta-lactam to usual therapy for MRSA bacteremia
Testosterone does not increase major adverse cardiac events, but does increase risk of AFib, PE, acute kidney injury, and arrhythmia (TRAVERSE)
For patients with chronic kidney disease, prehydration prior to contrast-enhanced computed tomography is unnecessary
Improved mortality with early initiation of RRT in critically ill patients
Clinical decision rule identifies AKI patients at low risk for hydronephrosis
Early initiation of RRT in critically ill patients with AKI does not lower 90-day mortality
No mortality difference between early and delayed initiation of renal replacement therapy in critically ill patients with AKI
Intraoperative hypotension but no major adverse events with continuation of perioperative RASIs
ACE + ARB does not improve outcomes in pts with T2DM with impaired renal function (VA NEPHRON)
No benefit from revascularization for asymptomatic renal artery stenosis (ASTRAL)
Less renal replacement therapy with sodium bicarbonate infusion for patients with severe metabolic acidosis
Individualized perioperative BP management reduces post-op complications
No benefit with restrictive fluid strategy during perioperative period for major abdominal surgery
No clear advantage to balanced crystalloids over saline; though 1 study suggests a mortality benefit in patients with sepsis
Intensive treatment of elevated blood pressure in hospitalized patients associated with adverse events
Final report from SPRINT: lowering SBP below 120 mm Hg decreases major adverse cardiac events and all-cause mortality
SBP of 120 instead of 140 in nondiabetic, high-risk elderly leads to significant benefits and some harms (SPRINT)
No differences in postoperative deaths or complications with stopping or continuing renin-angiotensin system inhibitors
Increased mortality with K <3.5 or >4.5 in patients hospitalized with acute MI
SBP of 120 instead of 140 in adults 75 years or older = significant benefits and some harms (SPRINT)
Rifaximin effective in decreasing post-TIPS hepatic encephalopathy in patients with cirrhosis
TAVR is as effective as surgical valve replacement for intermediate-risk patients with AS (PARTNER 2)
No benefit with use of periprocedural sodium bicarbonate or acetylcysteine in patients with CKD and angiography
Improved outcomes with complete revascularization in older adults with myocardial infarction (FIRE)
Three-day course of inhaled amikacin is effective in preventing ventilator-associated pneumonia
No difference with continuing vs stopping ACEIs or ARBs in adults who are undergoing major noncardiac surgery
Intensive BP control modestly decreased the likelihood of a broad composite of CV events, but with methodologic limitations
No benefit with balanced vs saline solution or slower vs faster rate for fluid resuscitation in ICU
Mortality risk is similar, but complications differ with TAVI and SAVR
No benefit to restrictive transfusion strategy for cardiac surgery patients