Acute coronary syndrome
229 results
1 - 100Presence of risk factors doesn't predict acute coronary syndrome
Clinical decision helpful in diagnosis of acute coronary syndrome in primary care
Patients with non-ST-elevation acute coronary syndromes do not need immediate intervention
Escitalopram reduces risk of adverse cardiac events in adults with depression and acute coronary syndrome
For treatment of acute coronary syndrome, prasugrel is better than ticagrelor at preventing recurrent MIs at 1 year
PSK9 inhibitor alirocumab reduces nonfatal MI in patients after acute coronary syndrome, but at high cost (ODYSSEY OUTCOMES)
Early CT angiography for suspected acute coronary syndrome reduces further ischemic testing; no effect on long-term clinical outcomes
After 1 month of DAPT after PCI for acute coronary syndromes, ticagrelor monotherapy results in similar outcomes with less bleeding than ticagrelor plus aspirin
Dabigatran associated with increased risk of coronary events
Ranolazine (Ranexa) not effective for ACS
Less bleeding with fondaparinux vs enoxaparin for ACS with PCI
Signs and symptoms not helpful in diagnosis of AMI/ACS
FDA: Clopidogrel/aspirin does not decrease overall mortality
Coronary CT angiogram allows for safe discharge of low-risk patients with chest pain
Faster discharge but more downstream testing with use of CCTA in ED
Additional testing of limited benefit in patients with new-onset chest pain
Pain severity does not predict outcomes with AMI
Intensive lipid lowering reduces mortality following ACS
Bivalirudin = abciximab + heparin for non-STEMI
For atrial fibrillation with ACS or PCI, apixaban plus clopidogrel (without aspirin) is preferred (AUGUSTUS)
Intensive lipid lowering adds additional benefit
Improved outcomes with early invasive strategy for ACS? Maybe, maybe not.
ED chest pain protocol is safe and efficient
Ruling out acute myocardial infarction based on patient characteristics
Low-dose rivaroxaban improves outcomes in patients with ACS (ATLAS)
Two-hour protocol identifies patients at low risk of ACS
Genotype-guided selection of oral P2Y12 inhibitor therapy no better than standard therapy after PCI for ACS or stable CAD
Mortality rate in patients with recent ACS and endoscopy is similar to that in patients with ACS and no endoscopy
Apixaban increases bleeding with no benefit in high-risk patients with ACS
No reduction in postdischarge medication errors after pharmacist-led intervention
Invasive strategy best only for men and high-risk women with unstable angina/non-ST elevation MI
Concomitant use of clopidogrel and a PPI may increase risk of adverse CHD outcomes
Early invasive therapy better for non-ST ACS
CCTA reduces need for hospitalization in low to moderate risk patients in ED
Better medication adherence with intervention; clinical outcomes unchanged
Clopidogrel + ASA no better than ASA alone for high-risk patients
Routine stress testing after negative biomarker testing seldom helpful