Beta-blockers for heart failure
36 results
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Beta-blockers don't decrease mortality in patients with AF + CHF
Post-MI beta-blockers do not decrease mortality
Perioperative beta-blockers = placebo for noncardiac surgery
For patients with acute myocardial infarction and normal ejection fraction, beta-blockers did not improve cardiovascular outcomes (REBOOT-CNIC)
Guideline for the management of heart failure: early prevention for patients at risk, quadruple therapy for those with symptoms
No benefit of beta-blockers for patients following acute myocardial infarction with normal ejection fraction
For patients with AMI and preserved ejection fraction, long-term beta-blockers do not improve outcomes (REDUCE-AMI)
Low-dose digoxin and bisoprolol are equally beneficial for rate control/QOL in patients with CHF and permanent AF (RATE-AF)
Diagnosing and managing acute heart failure Guidelines: NICE
Continued beta-blocker use after acute myocardial infarction (AMI) reduces hospitalizations but not cardiovascular death, AMI, or stroke
BNP monitoring + protocol improves HF outcomes
SGLT2 inhibitors optimal drug class for heart failure with preserved and mildly reduced ejection fraction
Eplerenone reduces mortality in NYHA II heart failure
Digitoxin reduces composite of hospitalization for heart failure or all-cause mortality for patients with NYHA class III or IV heart failure (DIGIT-HF)
BNP-guided therapy decreases heart failure mortality (BATTLESCARRED)
Rhythm control improves quality of life in patients with CHF and AF
CV interventions in old elderly are not useful (DEBATE)
Beta-blockers associated with improved morbidity/mortality in COPD patients
ACC/AHA guideline for the management of patients with chronic coronary disease
In patients with heart failure with a preserved ejection fraction, tirzepatide reduces hospitalizations and the need for urgent therapy but not mortality
Bedtime instead of morning ingestion of hypertension meds = significantly more reduction in cardiovascular disease risk
ACE = ARB for secondary CV prevention; combination worse (ONTARGET)
BNP-guided tx decreases CHF mortality
JNC 8 report on prevention/evaluation/treatment of hypertension
Lenient = strict rate control in prevention of adverse outcomes in AF
Antihypertensive therapy beneficial for patients with BP < 140/90 and history of CVD
Aficamten is more effective than metoprolol for improving symptoms of obstructive hypertrophic cardiomyopathy
BP target of 120 no better than 140 in T2DM (ACCORD)


