Oral fluoroquinolone or sulpha-trimethoprim in normal (UTI) doses is usually sufficient. Of the fluoroquinolones, ciprofloxacin and norfloxacin yield the highest concentrations. The duration of treatment is 4 weeks.
If the patient has fever and severe symptoms the initial treatment should consist of intravenous cefuroxime in a hospital for one week, followed by oral medication for 3 weeks.
Massage of the prostate is contraindicated.
Suprapubic cystostomy may occasionally be necessary to secure the emptying of the bladder. Do not catheterize.
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