- Dapagliflozin in high-risk T2DM reduces hospitalization for HF, but does not reduce death, MI, or stroke (DECLARE-TIMI 58)
- Rifaximin and some probiotics lessen symptoms in patients with IBS
- Testosterone therapy may reduce symptoms of depression in men
- Icosapent ethyl reduces risk of CV death in patients with CV disease, low LDL, and high triglycerides (REDUCE-IT)
- Marine n-3 (omega-3) fatty acids do not prevent cancer or cardiovascular disease events (VITAL)
- Online module promotes advance directives documentation
- Zoledronate 5 mg every 18 months reduces fragility fractures in women over 65 with osteopenia (NNT = 15 over 6 years)
- Ultrasound-assisted lumbar puncture more successful, less traumatic, less painful
- Limited meta-analysis suggests SGLT2 inhibitors improve cardiovascular outcomes in patients with T2DM + atherosclerosis
- Primary care patients often fail to disclose symptoms like anxiety, depression, fatigue, and sexual or relationship problems
- SR: poor-quality data suggests stem cell joint injections are safe, but of unclear benefit
- Vitamin D = placebo for preventing cognitive decline in African-American women with low vitamin D levels
- Prostatectomy reduces mortality compared with no surveillance in men with T2 cancer who presented with symptoms
- Strength training plus protein supplementation can delay or prevent frailty
- Clindamycin in BV-positive women at low risk for preterm delivery does not prevent adverse outcomes
- It takes up to 3 weeks for 90% of respiratory infections to resolve in kids
- Gabapentin may improve sexual function in women with vulvodynia
- Shorter courses of antibiotics for community-acquired pneumonia at least as good as longer courses
- Internet-based interventions curb problem drinking
- Risk of HIV transmission negligible if taking ART with viral load < 200 copies/mL
- Vitamin D is not effective as primary prevention of cardiovascular disease or cancer (VITAL)
EE+ POEM Archive