EE+ POEM Archive
- Better functional outcomes, more symptomatic bleeds with tenecteplase 4.5 to 24 hours after non-large vessel occlusion strokes (OPTION)
- Relative safety of assisted vaginal birth and second-stage cesarean delivery
- Decreased infection risk with alcohol-based chlorhexidine prior to intravascular catheter insertion
- The use of hair dye products is likely associated with an increased incidence of uterine fibromas among Black women
- No benefit of beta-blockers for patients following acute myocardial infarction with normal ejection fraction
- New clinical guideline provides classification scheme to triage adults with acute pulmonary embolism
- For patients with atrial fibrillation and a drug-eluting stent, monotherapy with apixaban or rivaroxaban is better than adding clopidogrel
- Optimal oxytocin dosing to prevent postpartum hemorrhage is 4 IU to 10 IU
- Olezarsen reduces triglyceride levels and the risk of acute pancreatitis in persons with severe hypertriglyceridemia
- Magnesium supplementation for slightly low levels is not associated with a reduction in tachyarrhythmias for critically ill patients
- For high-risk patients, high-dose inhaled corticosteroids reduce severe exacerbations more than moderate dose (NNT = 19)
- Group cognitive stimulation therapy may improve quality of life in people with dementia
- Decreased short-term mortality with steroid use for severe pneumonia and acute respiratory distress syndrome
- GLP-1 agonists improve short-term metabolic control and weight in children and adolescents with type 2 diabetes mellitus or obesity
- Ginkgo biloba may be effective for adults with chronic dizziness/vertigo of unclear etiology
- No difference in death or major ischemic events with postop liberal or restrictive postop transfusion (TOP)
- For patients with severe aortic stenosis and low surgical risk, TAVR provides better outcomes early but somewhat worse outcomes later (PARTNER 3)
- Remdesivir associated with lower mortality in hospitalized patients during Omicron era, especially if requiring supplemental oxygen
- THC, but not CBD, may offer some benefit to some for chronic pain
- Low, if any, risk of congenital malformations with Z-drug exposure in first trimester of pregnancy
- Slower, click-based titration of semaglutide increases tolerability
- Melatonin for adults with cognitive impairment: small improvements in cognition and sleep duration