EE+ POEM Archive
- Nearly 50% of children with severe asthma no longer meet the criteria for severe disease after 3 years
- Omalizumab is better than placebo in alleviating symptoms in kids with severe atopic dermatitis (ADAPT)
- Pragmatic trial: Oseltamivir of uncertain benefit in patients with flu-like symptoms
- Extended follow-up: anastrozole better than placebo to prevent breast cancer in high-risk women (IBIS-II)
- Melatonin is no more effective than placebo to prevent delirium after major cardiac surgery
- Physiotherapy plus usual care is equal to usual care in kids with functional constipation
- Whether warfarin is taken in the morning or the evening makes no meaningful difference in time in therapeutic range
- European guidelines on breast cancer screening 2020
- Acetaminophen (paracetamol) is no better than placebo for most pain, except maybe tension headache
- American College of Physicians: Limit testosterone supplementation in older men to the treatment of sexual function issues
- Elagolix with add-back therapy effective for premenopausal heavy menstrual bleeding associated with fibroids
- Folic acid and zinc supplementation does not improve semen quality or increase live birth rate
- Small reduction in CV outcome after ischemic stroke with lower LDL target, but also harms; no change in all-cause mortality
- A program involving family members reduces postoperative delirium in elderly patients
- Mailing FIT or gFOBT directly to patients increases uptake of colorectal cancer screening
- Ibuprofen postpartum does not increase blood pressure for women with mild hypertensive disorders of pregnancy
- Newborns with feeding difficulty may not need frenotomy
- Automated text reminders to take blood pressure medications do not improve hypertension control
- No clear advantage to balanced crystalloids over saline; though 1 study suggests a mortality benefit in patients with sepsis
- Increasing the D-dimer threshold for patients with low clinical pretest probability effectively rules out PE (PEGeD)
- No difference in unplanned secondary procedures after initial THA versus hemiarthroplasty for hip fractures in elderly
- Mohs similar to wide excision in observational study of patients with stage I melanoma (most < 0.8 mm thickness)