EE+ POEM Archive
- Overtreatment leads to harm in older patients with type 2 diabetes
- Intravenous immune globulin plus corticosteroids is the best initial therapy for multisystem inflammatory syndrome in children
- Platelet-rich plasma injection is no better than sham injection for midportion Achilles tendinopathy
- No-test medical abortion is safe and effective
- Clopidogrel monotherapy more effective than aspirin to prevent coronary events after PCI with drug-eluting stents (HOST-EXAM)
- Pimavanserin of uncertain benefit to treat psychosis in patients with dementia
- Limited data suggest that music improves sleep quality in older adults
- Cytisine unable to demonstrate noninferiority to varenicline, but is still an option for smoking cessation
- Rifaximin effective in decreasing post-TIPS hepatic encephalopathy in patients with cirrhosis
- Vaccines are only slightly less effective against the delta variant
- A single corticosteroid burst in children is associated with harms
- Gender-affirming hormone treatment in adolescents is not associated with thrombosis
- Tranexamic acid may reduce bleeding after cesarean delivery, but with a risk of adverse effects
- Active management is more effective than expectant management for resolution of nonviable pregnancy of unknown location
- Inhaled budesonide shortens duration of illness in high-risk outpatients with COVID-19 (PRINCIPLE)
- Provided infant carriers increase the rate of sustained breastfeeding
- Weekly tirzepatide + metformin better than daily insulin degludec + metformin in decreasing A1C, weight, and hypoglycemia (SURPASS-3)
- Weak correlation between umbilical cord blood gas values and neonatal outcomes
- Single-dose oral azithromycin not effective in the management of outpatient SARS-CoV-2 infection
- Fewer strokes but more bleeding with aspirin + either clopidogrel or ticagrelor than with monotherapy in secondary stroke prevention
- USPSTF 2021 recommends screening for gestational diabetes in asymptomatic pregnant persons at 24+ weeks (B recommendation)