EE+ POEM Archive
- Surgery for clavicular fractures provides better outcomes but more harms than conservative treatment
- MA: intra-articular corticosteroids provide short-term relief in patients with adhesive capsulitis
- Irbesartan slows aortic dilation, but doesn't reduce the rate of surgery in those with Marfan syndrome (AIMS)
- No cow's milk formula for the first 3 days of life prevents food allergies
- Counseling is equal to varenicline to help adolescents quit smoking
- Rates of adverse effects of treatment for otitis media varies by antibiotic and dose
- Useful signs and symptoms for diagnosing hip osteoarthritis
- Antibiotic use associated with a risk of cardiovascular disease in adult women
- Frozen embryo transfer associated with increased risk of childhood cancer
- USPSTF 2019 still recommends one-time AAA screening with US in men 65 years or older who have ever smoked (B recommendation)
- Vaccine prevents active tuberculosis in adults with latent tuberculosis (NNT = 333 over 3 years)
- Supplemental MRI screening in women with very dense breasts reduces interval cancer rate but may cause overdiagnosis (DENSE)
- Ubrogepant modestly effective for acute migraine, but safety and a lack of comparison with triptans are concerning
- MAb114 and REGN-EB3 preferred over ZMapp and remdesivir for the treatment of Ebola virus disease (PALM)
- Neonatal early-onset sepsis calculator associated with decreased antibiotic use and no increase in sepsis
- Comparable benefits and harms of anticoagulant and antiplatelet treatment in patients with PFO and cryptogenic stroke
- Unclear whether blue light is effective in treating acne vulgaris
- Risk prediction model predicts VTE recurrence after initial thrombotic event
- In patients with prior stroke and hypertension, lower BP target no more effective in preventing recurrent strokes (RESPECT)
- Another "-gepant"—ubrogepant —is somewhat effective for acute migraine (NNT = 13)