EE+ POEM Archive
- At-home transcranial direct current stimulation (tDCS) may be effective for moderate to severe depression
- Daily application of emollients reduces the risk of atopic dermatitis at 2 years of age
- In children 6-17 years old with episodic migraine, fremanezumab reduces migraine days more than placebo
- One-year outcomes are better in children with acute appendicitis who are initially treated with surgery instead of antibiotics
- For very-high-risk patients, evolocumab reduces myocardial infarction (NNT = 71) and revascularization (NNT = 42) over 4.6 years (VESALIUS)
- Duloxetine may be effective for refractory chronic cough
- Tirzepatide is at least as effective as dulaglutide at reducing cardiovascular events in patients with Type 2 diabetes (SURPASS-CVOT)
- Rivaroxaban is no better than aspirin after catheter ablation for atrial fibrillation at least 1 year earlier (OCEAN)
- Stenting (but not endarterectomy) reduces the risk of stroke or death over 3.6 years in asymptomatic, high-grade carotid stenosis
- GLP-1 receptor agonist discontinuation associated with increased incidence of excess weight gain in pregnancy
- RSV vaccine slightly reduces hospitalization risk in adults 60 and older (NNT = 4130)
- More than half of adults treated with antibiotics for acute appendicitis do not require appendectomy at 10 years (APPAC)
- Monotherapy with ibuprofen is optimal for children with acute nonoperative musculoskeletal injuries
- Topical imiquimod may be a reasonable alternative to excision for treatment of vulvar intraepithelial neoplasia
- Estrogen replacement therapy does not increase cardiovascular risk except in people 70 years or older
- Prenatal exposure to acid-suppressive meds not associated with risk of neuropsychiatric disorders in children
- Zoliflodacin and ceftriaxone plus azithromycin have comparable cure rates in patients with uncomplicated urogenital gonorrhea
- Cast immobilization and surgery have similar 5-year outcomes in patients with minimally displaced fractures of the scaphoid waist
- Scheduled early-term birth for patients with increased risk of term pre-eclampsia is associated with risk reduction
- Age-adjusted D-dimer is accurate for diagnosis of deep vein thrombosis and can the reduce need for further imaging
- Higher rate of blood pressure control associated with simultaneously addressing adherence and intensification of treatment
- In older adults with cardiovascular disease, SGLT2 inhibitors significantly decrease all-cause mortality, cardiovascular events, and heart failure events