EE+ POEM Archive
- Study confirms benefits of early administration of oseltamivir for hospitalized patients with influenza
- Low-certainty evidence shows some benefit of melatonin use in the intensive care unit
- Personalized messages regarding colorectal cancer risk do not increase the uptake of screening
- Clopidogrel is slightly more effective than aspirin for the secondary prevention of cardiovascular and cerebrovascular events
- Even moderate amounts of imaging with ionizing radiation are associated with a significant increase in the risk of hematologic cancer in children
- Long-term use of vaginal pessary self-management continues to be effective and cost effective (TOPSY)
- Sodium supplementation as an adjunct to furosemide in acute decompensated heart failure leads to weight loss and decreased length of stay
- Digitoxin reduces composite of hospitalization for heart failure or all-cause mortality for patients with NYHA class III or IV heart failure (DIGIT-HF)
- Time-restricted eating with exercise does not affect glycemic control during pregnancy
- Transcutaneous auricular vagal stimulation may improve pain and constipation in adults with irritable bowel syndrome with constipation
- Immature-to-total neutrophil ratio is most accurate complete blood count parameter for sepsis in neonates, but still not enough to diagnose
- No evidence for an increased risk of suicide or self-harm events in adults who use GLP-1 receptor agonists
- American College of Physicians reaffirms de-emphasis on glucose control and adds new treatments for type 2 diabetes
- Lipid-lowering agents are not associated with an increased risk of developing dementia
- Clesrovimab reduces risk of respiratory syncytial virus infection and hospitalization (NNT = 51); unclear if it's better than nirsevimab (CLEVER)
- A calorie-restricted Mediterranean diet, with plenty of exercise, might help prevent diabetes in some older adults
- COVID-19 vaccines are still effective at reducing emergency department visits, hospitalizations, and (especially) mortality
- Clinical markers that predict severe postpartum bleeding associated with maternal mortality or severe morbidity
- Cumulative amount of aluminum received via vaccines is not related to an increase in disorders of early childhood
- For post-stent patients with atherosclerotic coronary vascular disease who are taking an anticoagulant, adding aspirin worsens outcomes (AQUATIC)
- Respiratory syncytial virus vaccine does not reduce the risk of all-cause cardiovascular disease hospitalization (DAN-RSV)
- 17% of elderly adults who receive medications for severe agitation experience adverse effects; midazolam is the worst (58%)