EE+ POEM Archive
- Ensitrelvir reduces the risk of COVID-19 in household contacts (NNT = 16)
- High-dose influenza vaccination is associated with a lower risk of Alzheimer dementia than standard-dose vaccination
- Semaglutide decreases heavy drinking in obese adults who seek treatment for alcohol use disorder
- Increased functional independence with thrombectomy for moderate-to high severity stroke due to medium vessel occlusion (ORIENTAL MeVO)
- Metoclopramide and low-dose erythromycin may be most effective for gastroparesis symptoms
- mRNA influenza vaccine from Moderna is slightly more effective (NNI = 125) but with more injection-site reactions and systemic symptoms
- Limited evidence for probiotics as adjunct treatment for vulvovaginal candidiasis
- A vibrating cool pack device plus video game distraction decreases postvaccination presyncope in young adolescents
- Low doses of spironolactone for primary aldosteronism are better tolerated by men than high doses
- Transcranial magnetic stimulation may be effective in children with autism and severe communication limitations
- An upper lip/maxillary frenulum is unlikely to cause breastfeeding problems
- Prenatal acetaminophen exposure is not associated with autism or attention deficit in sibling matched cohort
- Breathing exercises may be an effective addition for asthma control
- Better functional outcomes with early dual antiplatelet therapy for patients receiving intravenous thrombolysis for stroke
- Point-of-care testing for 23 respiratory pathogens does not reduce overall rate of antibiotic use or improve outcomes
- Fluvoxamine but not metformin is effective for reducing fatigue following COVID-19 infection (REVIVE-TOGETHER)
- Multicomponent nonpharmacologic (but not single-component or pharmacologic) interventions decrease the duration of delirium in older adults
- NAD+ supplements lack clear evidence of benefit
- Bone biopsy performs no better than ulcer bed biopsy to guide antibiotic selection for diabetic foot osteomyelitis
- Digoxin reduces new-onset or worsening heart failure in adults with symptomatic rheumatic heart disease
- Selective decontamination of the digestive tract in mechanically ventilated patients does not decrease in-hospital deaths