EE+ POEM Archive
- For chronic pain treatment, buprenorphine is not thought of as a better option by many patients and is no more effective than full agonist opioids
- Intraoperative hypotension but no major adverse events with continuation of perioperative RASIs
- Catheter-collected urine dipstick can identify or rule out urinary tract infection in febrile infants 2 to 6 months of age
- Practice guideline: Do not use injections or radiofrequency to treat chronic neck or low back pain
- Poor-quality studies show dextromethorphan-bupropion associated with a greater likelihood of clinical remission and response in depressed adults
- Bladder health in women in the United States
- Baloxavir does not significantly reduce symptomatic flu among unvaccinated household contacts
- Mepolizumab provides only a small reduction in moderate exacerbations when added to triple inhaler therapy for eosinophilic COPD (MATINEE)
- In older adults with chronic insomnia, mirtazapine improves sleep, but many people don't tolerate it (MIRAGE)
- What are the comparative benefits of available treatments for acute migraine pain?
- Intermittent fasting 3 days a week results in slightly more weight loss than daily caloric restriction
- Multicancer early detection numbers needed to screen: 1000 to detect one stage 1 or 2 cancer, 530 to detect any cancer (SPOT-MAS)
- Good evidence that duloxetine, milnacipran, and pregabalin provide meaningful pain reduction in adults with fibromyalgia
- Causes of and risk factors for postpartum hemorrhage
- American College of Physicians urges caution when patients want to use cannabis/cannabinoids to treat chronic noncancer pain
- Comparable cure rates with oral gepotidacin and ceftriaxone + azithromycin for uncomplicated urogenital gonorrhea (EAGLE-1)
- Immunoglobulin alone is noninferior to immunoglobulin plus aspirin for Kawasaki disease
- Real-world data don’t support new Alzheimer’s disease diagnostic criteria
- Awake prone positioning improves survival without intubation in patients with COVID-19 and acute hypoxemic respiratory failure
- Amiloride is noninferior to spironolactone for resistant hypertension
- Bedtime vs morning administration of antihypertensives equally safe with no difference in adverse CVD risk (BedMed)
- Sound masking, cognitive behavior therapy, and patient education may help tinnitus symptoms
- Wound vacs are no better than usual care in promoting healing of surgical wounds