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  • Zanamivir slightly decreases flu symptom duration; prophylaxis is more effective
  • Ziresovir does not provide a clinically meaningful reduction in symptom severity in hospitalized infants with respiratory syncytial virus at 3 days
  • Zoledronate 5 mg every 18 months reduces fragility fractures in women over 65 with osteopenia (NNT = 15 over 6 years)
  • Zoledronate given twice 5 years apart to women with normal bone density or osteopenia reduces fracture risk (NNT = 9 over 10 years)
  • Zoledronic acid reduces asymptomatic fractures but not clinical ones in men
  • Zoledronic acid reduces fracture risk in osteoporosis, osteopenia with previous fracture
  • Zoledronic acid reduces fractures, mortality after hip fracture (HORIZON)
  • Zolpidem associated with adverse pregnancy outcomes
  • Zonisamide + counseling causes weight loss, side effects
  • Zoster vaccine not associated with increased risk of HZ infection in immune-mediated disease patients
  • “Laugh therapy” is at least as effective as lubricant drops for dry eye disease
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