EE+ POEM Archive
- Vaccine prevents active tuberculosis in adults with latent tuberculosis (NNT = 333 over 3 years)
- Vaccine safe and effective for prevention of EV71 disease (NNT = 50 over 1 year)
- Vaccines are only slightly less effective against the delta variant
- Vaccines for rotavirus increase risk of intussusception slightly
- Vaginal bleeding decreases over time with a levonorgestrel intrauterine system
- Vaginal misoprostol superior to buccal route for cervical ripening at term pregnancy
- Vaginal pessary plus pelvic floor exercises more effective than exercises alone for pelvic organ prolapse
- Vaginal progesterone = placebo in preventing preterm birth and improving neonatal and childhood outcomes (OPPTIMUM)
- Vaginal progesterone does not lessen preterm birth for high-risk women
- Vaginal progesterone is most beneficial for the prevention of preterm birth in women at high risk
- Vaginal progesterone not beneficial after arrest of preterm labor (PROMISE)
- Vaginal swabs are slightly more sensitive than urine samples for detecting chlamydia, gonorrhea, or trichomoniasis in women
- Valaciclovir decreases the frequency of vertical transmission among pregnant women with primary cytomegalovirus infection
- 9-valent HPV vaccine offers only small advantage over quadrivalent vaccine
- Validated clinical decision rule to guide management for patients with suspected influenza
- Validation of a 1-hour algorithm to rule in or rule out acute myocardial infarction
- Validation of approach to patient with suspected heart failure (MICE rule)
- Valproate in pregnancy causes cognitive impairment in infants
- Valsartan/sacubitril reduces mortality more than enalapril 10 mg twice daily in patients with heart failure (PARADIGM-HF)
- Valsartan does not improve clinical outcomes in impaired glucose tolerance (NAVIGATOR)
- Value of surveillance in patients with low-risk polyps is uncertain
- Vancomycin + piperacillin-tazobactam associated with greater mortality than vancomycin + cefepime in patients with sepsis
- Vancomycin > metronidazole for severe C. difficile-associated diarrhea
- Vancomycin better than metronidazole for reducing mortality risk from severe C difficile infection
- Vancomycin plus rifampicin effective in treatment of nosocomial MRSA pneumonia
- VapoRub improves URI symptoms at night in children
- Varenicline, bupropion, nicotine replacement all effective for smoking cessation
- Varenicline, bupropion may not increase risk of cardiovascular events
- Varenicline (Chantix) effective for smoking cessation
- Varenicline (Chantix) not associated with increased CV events
- Varenicline effective for improving vaping cessation rate in adults
- Varenicline effective for smokers preferring to "cut down" rather than quit "cold turkey"
- Varenicline effective for smoking cessation
- Varenicline increases risk of adverse CV events
- Varenicline increases smokeless tobacco cessation
- Varenicline plus bupropion SR no better than varenicline alone for tobacco cessation
- Varenicline plus nicotine replacement therapy more effective than varenicline alone
- Varenicline similar in effectiveness to nicotine patch
- Varicella immunity wanes in children after 5 years
- Various quality improvement strategies decrease injurious falls in the elderly
- Vasoactive agents lower mortality in patients with acute variceal bleeds
- Vasodilators of little use with aortic insufficiency
- Vasopressin, steroids, and epinephrine improve in-hospital cardiac arrest survival
- VBAC with prior vaginal delivery safer than cesarean
- Venous samples are a less-painful starting point for the evaluation of patients with AECOPD
- Vericiguat for heart failure reduces hospitalization, but not mortality
- Vertebroplasty = sham procedure for compression fractures
- Vertebroplasty improves pain of acute osteoporotic fractures (VAPOUR)
- Vertebroplasty ineffective for painful osteoporotic fractures
- Vertebroplasty marginally better than usual care for compression Fx (Vertos II)
- Vertebroplasty no more effective than sham treatment for compression fracture
- Very expensive lefamulin is no worse than moxifloxacin for community-acquired pneumonia
- Very few patients with syncope have pulmonary emboli
- Very low incidence of acute myocarditis after mRNA COVID-19 vaccination in young adults
- Vestibular rehabilitation is beneficial for patients who have balance problems after stroke
- Vibegron effective versus placebo but not tolterodine for adults with overactive bladder symptoms (EMPOWUR)
- Video laryngoscopy is more likely to be successful on initial attempt in urgent intubation of newborns
- Virtual colonoscopy avoids the need for bowel prep
- Virtual delivery of pain-coping skills does not decrease opioid use or improve function
- Virtual reality decreases cancer-related pain more than 2-dimensional guided imagery in hospitalized adults
- Viscous dietary fiber supplementation decreases HbA1c and fasting blood glucose in patients with type 2 diabetes
- Viscous lidocaine = placebo in children with mouth ulcers in the ED
- Visual assessment unreliable in estimating bilirubin levels in infants
- Visual field testing by confrontation not accurate
- Vitamin B12 effective in treatment of recurrent aphthous stomatitis
- Vitamin C and E do not prevent preeclampsia
- Vitamin C has negligible effect on uric acid in patients with gout
- Vitamin C plus iron supplementation is no better than iron alone for iron-deficiency anemia
- Vitamin C prevents RSD in patients with wrist fracture
- Vitamin D, at high doses, prevents fractures
- Vitamin D, in high doses, prevents falls
- Vitamin D, omega-3 fatty acids, and strength training not beneficial for elderly without major comorbidities (DO-HEALTH)
- vitamin D + calcium = placebo for cognitive decline (WHI)
- Vitamin D = placebo for preventing cognitive decline in African-American women with low vitamin D levels
- Vitamin D3 does not prevent treatment failure in asthmatic adults with low vitamin D levels
- Vitamin D and/or fish oil supplementation do not reduce the risk of atrial fibrillation (VITAL)
- Vitamin D does not affect isolated systolic hypertension
- Vitamin D does not decrease pain or headache more than placebo
- Vitamin D does not prevent ARTI or asthma exacerbation in vitamin D–deficient patients
- Vitamin D does not reduce knee pain from osteoarthritis
- Vitamin D does not reduce mortality in adults with advanced heart failure
- Vitamin D does not reduce pain in adults with symptomatic knee osteoarthritis
- Vitamin D does not reduce the incidence nor the recurrence of depression in adults
- Vitamin D does not reduce the incidence or severity of URIs in healthy adults
- Vitamin D is not effective as primary prevention of cardiovascular disease or cancer (VITAL)
- Vitamin D not effective for reducing asthma exacerbations in children with asthma and low vitamin D levels (VDKA)
- Vitamin D plus calcium does not reduce cancer risk in postmenopausal women
- Vitamin D prevents falls in the elderly
- Vitamin D reduces risk of parent-reported wheezing in first year among preterm black infants
- Vitamin D replacement increases blood levels but doesn't affect fatigue
- Vitamin D supplementation: good for bones and fall prevention, but little else
- Vitamin D supplementation does not improve survival in adults with digestive tract cancers
- Vitamin D supplementation does not prevent diabetes
- Vitamin D supplementation during pregnancy does not prevent asthma in offspring
- Vitamin D supplementation slightly reduces diabetes diagnosis in at-risk adults
- Vitamin E = placebo for relief of neuropathic symptoms in patients with diabetes (VENUS)
- Vitamin E and metformin do not reduce liver enzyme levels in pediatric nonalcoholic fatty liver disease
- Vitamin E associated with congenital heart defects
- Vitamin E improves histology of NASH, patient-oriented benefit unknown
- Vitamin E supplementation increases risk of prostate cancer
- Vitamin K supplementation improves stability of anticoagulation
- Vitamins, antioxidants do not prevent CV disease
- Vitamins C and E ineffective for PIH
- Vitamins E and C and selenium do not reduce risk of prostate or total cancer in men
- Vitamins E and C do not reduce CVD risk in men
- Vitamin suppls do not reduce risk of skin cancer occurrence or recurrence
- Volume-based low-dose CT screening reduces lung cancer–specific mortality (NELSON)
- Vorapaxar has benefits but increases risk of serious bleeding
- VTE: Up to 10% with unexplained embolus will have cancer
- VTE recurrence higher in men