EE+ POEM Archive
- Radial artery grafts reduce risk of revascularization compared with saphenous vein graft in CABG
- Radial ESWT improves pain in chronic plantar fasciitis
- Radial extracorporeal shock wave therapy = exercise = custom orthotics and advice for plantar fascia pain
- Radial extracorporeal shock wave therapy = sham therapy for subacromial shoulder pain
- Radiofrequency = cryoballoon for pulmonary vein ablation to treat atrial fibrillation
- Radiofrequency ablation an option for healthy younger patients with paroxysmal AF
- Radiofrequency ablation reduces risk of neoplastic progression with BE and low-grade dysplasia
- Radiofrequency catheter ablation superior to drug treatment for paroxysmal AF
- RA factors + CVD risk factors modestly accurate in predicting CVD events in patients with RA
- Raloxifene and tamoxifen equally effective in reducing breast CA risk
- Raloxifene decreases breast CA risk, no effect on CVD risk (RUTH)
- Ramelteon reduces risk of delirium in hospitalized patients
- Ramipril increases pain-free walking time in patients with intermittent claudication
- Ramipril increases walking distance, has no effect on QOL in pts with claudication
- Ranolazine (Ranexa) not effective for ACS
- Ranolazine adds little to maximum antianginal therapy (ERICA)
- RA options: MTX still first-line
- Rapid accurate assessment of delirium in older ED patients
- Rapid antigen test for yeast more sensitive than wet mount
- Rapid antigen test reduces antibiotic use in adult sore throat
- Rapid antigen tests for COVID-19 are much less sensitive in asymptomatic persons (40% vs 80% in symptomatic persons)
- Rapid HbA1C testing doesn't improve outcomes or save money
- Rapid identification of viral respiratory infection is possible
- Rapid influenza tests reduce ER testing in kids, little else
- Rapid response teams decrease non-ICU arrest, no effect on hospital mortality
- Rapid test (Xpert MTB/RIF) very accurate for drug resistant TB
- Rasagiline may be neuroprotective in PD
- Rate and rhythm control both effective in managing post-op atrial fibrillation
- Rate of new-onset seizures is less than 0.01% among SARS-CoV-2 vaccine recipients and placebo recipients
- Rate of UTIs in pts using special catheters = rate using standard catheters
- Rate of VTE after hip replacement is less than 1%
- Rates of adverse effects of treatment for otitis media varies by antibiotic and dose
- Ratio of AFP in vaginal blood to maternal serum is a marker for pregnancy failure
- RCT: In older persons, aspirin increases the risk of metastatic or stage 4 cancers and cancer mortality (ASPREE)
- Reading to young children may reduce social and emotional problems later in their lives
- Real acupuncture slightly more effective than sham for chronic low back pain
- Real-world study finds lower mortality and stroke risk with dabigatran, but more GI bleeds
- Rear-facing child car seats for children younger than 4 years
- Reasoning training slows age-related functional decline
- Rebound symptoms common with COVID-19 even after placebo treatment
- Reboxetine ineffective for depression
- Recent studies of OTC products favor polyethylene glycol and senna for treating chronic constipation
- Recombinant herpes zoster vaccine highly effective
- Recombinant human activated Protein C does not reduce mortality in patients with septic shock (PROWESS-SHOCK)
- Recombinant human prourokinase is comparable with alteplase in treatment of acute ischemic stroke (PROST)
- Recommendations for care outpace the time available for a typical primary care practice
- Rectal = oral acetaminophen for fever control or analgesia
- Recurrence of shoulder dislocation reduced by immobilization in external rotation with abduction
- Recurrence rate and predicting factors for recurrent instability after traumatic shoulder dislocation
- Recurrent herpes zoster more common in women, younger adults, and the immunosuppressed
- Red hot chili peppers do not worsen hemorrhoid symptoms
- Reduced all-cause mortality associated with post-fracture bisphosphonate treatment
- Reduced antibiotic prescribing guided by CRP testing does not worsen outcomes in nursing home patients
- Reduced labor duration and pain with the guided use of a Swiss ball in active labor
- Reduced readmissions with home NIV plus oxygen for COPD exacerbation with persistent hypercapnia
- Reduced sensitivity of blood cultures after initiating antibiotics for severe sepsis
- Reducing homocysteine not beneficial in advanced chronic kidney disease
- Reducing iron stores does not benefit patients with peripheral arterial disease
- Reduction in emergency department visits and readmissions with postpartum hypertension management protocol
- Refeeding syndrome is associated with a higher risk of 6-month mortality
- Reflexology of uncertain clinical benefit
- Regional anesthesia improves success of external cephalic version
- REGN-COV2 monoclonal antibody cocktail may reduce the need for a medically attended visit for outpatients with COVID-19
- Regular, moderately intense exercise during pregnancy is beneficial
- Regular multivitamin use is not associated with a mortality benefit
- Regular sauna bathing reduces cardiovascular disease risk
- Relapse of depression more likely after discontinuation of medication (number needed to treat to harm = 6).
- Relaxed hemoglobin A1c goals for T2DM from the American College of Physicians
- Reliability of some clinical exam findings is dubious in children with suspected pneumonia
- Religious coping associated with increased use of life-prolonging care near death
- Relugolix plus estradiol plus norethindrone reduces heavy menstrual bleeding due to fibroids (LIBERTY 1 and 2)
- Remission or recovery common after a first episode of psychosis
- Remission rate for unresponsive major depression modestly higher with added aripiprazole
- Renin angiotensin system inhibitors not useful for CAD without CHF
- Repair undescended testis before age 13
- Repeat BMD testing: little, if any, value in elderly men and women
- Repeat cytology within 6 months = colposcopy for younger women with ASCUS or LSIL
- Repeated antenatal doses of steroids reduces neonatal morbidity (ACTORDS)
- Repolarization abnormality in athletes is risk factor for cardiomyopathy
- Reporting estimated glomerular filtration rate (GFR) may not improve outcomes
- Rescreening after initial negative colonoscopy may be extended beyond 10 years
- Respiratory tract symptoms in children last longer than expected
- Responders to atomoxetine do fine with lowered doses
- Restarting anticoagulants after ICH associated with fewer thromboembolic events
- Restrained Lyme disease management guidelines from 3 US specialty societies
- Restriction of sodium may be harmful for patients with cardiovascular disease
- Restrictive transfusion strategy = liberal strategy for long-term mortality (FOCUS)
- Restrictive transfusion strategy for patients with AMI and anemia is comparable with liberal strategy; more research needed
- Restrictive transfusion strategy improves outcomes in acute upper GI bleeding
- Restrictive transfusion strategy increases cardiac events in patients undergoing orthopedic surgery
- Restrictive transfusion strategy is best for hospitalized patients
- Results of fecal immunochemical tests for colorectal cancer screening not affected by NSAIDs, aspirin, or anticoagulants
- Resuming oral anticoagulants after a bleed is associated with fewer thrombi and deaths, but more bleeds
- Reteplase is slightly more effective than alteplase at achieving good neurologic outcome at 90 days after ischemic stroke
- Reward-based financial incentives are effective for smoking cessation
- Rh testing and treatment are unnecessary after induced first-trimester abortion
- Rhythm control improves quality of life in patients with CHF and AF
- Rhythm control is associated with a lower risk of cognitive decline than rate control in adults with atrial fibrillation
- Rhythm control no better than rate control in AF + CHF
- Rifabutin added to combination therapy might be a new option for treating H. pylori infection
- Rifampin for 4 months preferred to isoniazid for 9 months for latent TB in high-risk patients
- Rifaximin and some probiotics lessen symptoms in patients with IBS
- Rifaximin effective in decreasing post-TIPS hepatic encephalopathy in patients with cirrhosis
- Rifaximin prevents recurrent hepatic encephalopathy
- Rifaximin somewhat helpful for nonconstipation IBS
- Rimegepant somewhat effective for acute migraine (NNT = 13)
- Rimonabant: weight loss at risk of serious adverse events
- Riociguat marginally effective for pulmonary hypertension
- Risedronate decreases fracture rate in children with osteogenesis imperfecta
- Risk-based use of CRP preferred for acutely ill children
- Risk factors + symptoms to diagnose knee OA (EULAR guidelines)
- Risk factors for progression of BE to cancer or HGD
- Risk of atypical femoral fracture higher with longer duration of bisphosphonate use and in other groups of women
- Risk of cancer is low in patients with Barrett's esophagus
- Risk of GI bleeding highest with rivaroxaban, lower with apixaban… and lowest with PPI cotherapy
- Risk of HIV transmission negligible if taking ART with viral load < 200 copies/mL
- Risk of lymphoma not increased among patients with inflammatory bowel disease
- Risk of major depressive disorder high after traumatic brain injury
- Risk of melanoma increases minimally, if at all, with the use of PDE5 inhibitors
- Risk of permanent parkinsonism increased in patients with chronic renal failure
- Risk of recurrent venous thromboembolism is 3% in patients with subsegmental pulmonary embolism who are not anticoagulated
- Risk of serious bacterial infection low in recently immunized febrile infants
- Risk of serious maternal morbidity with multiple cesarean deliveries
- Risk of serious pneumonia in COPD patients using inhaled corticosteroids
- Risk of severe hypoglycemia similar between different insulin formulations
- Risk of stroke after TIA is 2.8% at 1 month and 5.1% at 1 year
- Risk of subsequent advanced adenoma or CRC in patients with low-risk adenoma on baseline colonoscopy
- Risk prediction model predicts VTE recurrence after initial thrombotic event
- Risk score app accurately classifies COVID-19 outpatients who do not require testing or imaging
- Risk score predicts likelihood of requiring surgery for asymptomatic AS
- Risks factors for bone loss with DMPA
- Risperidone and paliperidone are less effective and more harmful than shown in published studies
- Rivaroxaban + aspirin somewhat better than aspirin alone for tertiary prevention of CVD (COMPASS)
- Rivaroxaban + clopidogrel causes somewhat less bleeding than triple therapy in patients with AF undergoing PCI
- Rivaroxaban effective for acute DVT (EINSTEIN)
- Rivaroxaban is effective and safe for thromboprophylaxis after bariatric surgery
- Rivaroxaban is noninferior to warfarin for valvular atrial fibrillation; also associated with fewer strokes
- Rivaroxaban reduces acute limb ischemia, but increases major bleeds after revascularization for PAD (VOYAGER PAD)
- Rivaroxaban similar to warfarin for patients with NVAF
- Rofecoxib, diclofenac and indomethacin increase risk of CVD
- Romiplostim safe, effective, and very expensive treatment for ITP
- Romosozumab prevents clinical fracture slightly better than alendronate in women with osteoporosis and previous fracture
- Rosiglitazone associated with increased risk of acute MI
- Rosiglitazone delays developing DM (DREAM)
- Rosiglitazone increases MI risk
- Rosiglitazone more likely to succeed as monotherapy but POEMs lacking
- Rosuvastatin does not improve outcomes in HF with average lipids
- Rosuvastatin has no effect on clinical outcomes in CHF
- Rosuvastatin prevents DVT at very high cost
- Rotating night shift work increases risk of CHD in women
- Rounding first on discharging patients does not lead to earlier discharge times or shorter length of stay
- Routine administration of tranexamic acid to prevent postpartum hemorrhage is of minimal benefit
- Routine BV screening not recommended during pregnancy (USPSTF)
- Routine CT scans for occult malignancy not useful in patients with unprovoked VTE
- Routine MRI reports for low back pain may decrease function and worsen pain because of Catastrophizing language
- Routine oxygen supplementation after acute stroke does not improve functional outcomes
- Routine replacement of IVs in hospitalized patients is unnecessary
- Routine replacement of peripheral intravenous catheters is associated with fewer bloodstream infections
- Routine stress testing after negative biomarker testing seldom helpful
- Routine stress testing after PCI not necessary in adults with diabetes (POST-PCI)
- Routine weighing during pregnancy does not prevent excessive weight gain
- RSV: Steroid treatment does not decrease wheezing
- RSV vaccine is safe and effective in adults 60 years and older, but the absolute risk reduction is small
- Rules for strep throat validated
- Ruling out acute myocardial infarction based on patient characteristics
- Rural Black women who are given the option of home HPV sampling are more likely to get screened