- Dabigatran Versus Vitamin K Antagonists In Non-valvular Atrial Fibrillation
- Daily Iron Supplementation For Improving Prevalence Of Anaemia And Iron Status In Menstruating Women
- Daily Oral Iron Supplementation During Pregnancy
- Danazol For Cyclical Mastalgia
- Danazol For Heavy Menstrual Bleeding
- Danazol For Unexplained Infertility
- Danazol In The Treatment Of Endometriosis
- Dapsone As An Oral Corticosteroid Sparing Agent For Asthma
- Darbepoetin For The Anaemia Of Chronic Kidney Disease
- Day Care Versus In-patient Surgery For Age-related Cataract
- Day-case Versus Overnight Stay In Laparoscopic Cholecystectomy
- Day Hospital Versus Admission For Acute Psychiatric Disorders
- D-dimer Testing And Pulmonary Embolism
- Debridement For Surgical Wounds
- Debridement Of Chronic Wounds
- Debridement Of Diabetic Foot Ulcers
- Decision Aids For Patients Facing Health Or Screening Decisions
- Decompressive Craniectomy For High Intracranial Pressure In Traumatic Brain Injury
- Decompressive Surgery For Treating Nerve Damage In Leprosy
- Decongestants And Antihistamines For Acute Otitis Media In Children
- Decubitus Ulcer On The Heel - Image
- Deep Brain And Cortical Stimulation For Epilepsy
- Deep Brain Stimulation For Parkinson Disease
- Deep Endemic Mycoses
- Deep Vein Thrombosis
- Deep Vein Thrombosis - Related Resources
- Deep Venous Thrombosis (compression Ultrasonography) - Video
- Deep Venous Thrombosis In Femoral Vein (compression Ultrasonography) - Video
- Deep Venous Thrombosis Prophylaxis In Cancer Patients
- Deer Fly Bite On The Scalp - Image
- Defibrillation By Basic Emergency Medical Technicians In Patients With Out-of-hospital Cardiac Arrest
- Deformity Of The Toes With Accompanying Onychogryphosis - Image
- Dehumidifiers For Chronic Asthma
- Dehydroepiandrosterone (DHEA) For Schizophrenia
- Dehydroepiandrosterone (DHEA) For Systemic Lupus Erythematosus (SLE)
- Delayed Antibiotic Prescribing For Acute Otitis Media In Children
- Delayed Antibiotics For Respiratory Infections
- Delayed Prescribing For Acute Conjunctivitis
- Delayed Prescribing For Acute Lower Respiratory Tract Infection
- Delay To Institution Of Therapy And Induction Of Remission Using Single-drug Or Combination Antirheumatic Drug Therapy In Early Rheumatoid Arthritis
- Delirium In The Elderly
- Delirium In The Elderly - Related Resources
- Dengue Skin Rash - Image
- Dental Abrasion - Image
- Dental Attrition - Image
- Dental Caries And Other Diseases Of The Hard Tissues Of The Teeth And Dental Pulp
- Dental Caries And Other Diseases Of The Hard Tissues Of The Teeth And Dental Pulp - Related Resources
- Dental Caries - Image
- Dental Enamel Hypoplasia In APECED - Image
- Dental Erosion - Image
- Dental Fistula In The Chin - Image
- Dental Traumas
- Dental Traumas - Related Resources
- Depot Medroxyprogesterone Versus Norethisterone Oenanthate For Long-acting Progestogenic Contraception
- Depot Risperidone For Schizophrenia
- Depression
- Depression, Drugs And Somatic Diseases
- Depression, Drugs And Somatic Diseases - Related Resources
- Depression And Other Psychiatric Disorders - Related Resources
- Depression In Mothers Bringing Their Offspring For Evaluation Or Treatment Of Depression
- Depression In Old Age
- Depression In Old Age - Related Resources
- Depression Of Adolescents
- Depression Of Adolescents - Related Resources
- Depression - Related Resources
- De Quervain's Disease: Surgical Or Nonsurgical Treatment?
- De Quervain's Disease And Other Tendinitides Of The Wrist And Forearm
- De Quervain's Disease And Other Tendinitides Of The Wrist And Forearm - Related Resources
- Dermatitis Herpetiformis On The Buttocks - Image
- Dermatitis Herpetiformis On The Knees - Image
- Dermatitis Herpetiformis On The Skin Of The Elbow Region - Image
- Dermatofibroma - Image
- Dermatofibroma - Image (2)
- Dermatofibroma - Image (3)
- Dermatofibroma In The Leg - Image
- Dermatological Diagnosis At A Glance
- Dermatomycoses
- Dermatomycoses - Related Resources
- Dermatosis In The Medial Aspect Of The Foot - Image
- Dermographism - Image
- Dermographism - Image (2)
- Dermographism On The Shoulder - Image
- Desferrioxamine Mesylate For Iron Overload In Transfusion-dependent Thalassaemia
- Desmoplastic Trichoepithelioma - Image
- Desmopressin For Minimising Perioperative Allogeneic Blood Transfusion
- Desmopressin For Nocturnal Enuresis In Children
- Desquamative Gingivitis - Image
- Detached Retina
- Detached Retina - Related Resources
- Detecting Breast Implant Rupture
- Detecting Hydrops Of The Knee - Video
- Detection, Adherence And Control Of Hypertension For The Prevention Of Stroke
- Detection Of Coins Ingested By Children Using A Handheld Metal Detector
- Determining The Age Of Bruises In Children
- Determining The Direction Of Skin Folds Before Minor Surgery - Video
- Determining The Position Of The Patella - Image
- Determining The Type Of Urinary Incontinence On The Basis Of Bladder Stress Test
- Determining The Type Of Urinary Incontinence On The Basis Of History-taking And Physical Examination
- Determining The Volume Of Residual Urine By Ultrasonography
- Detoxification Treatments For Opiate Dependent Adolescents
- Developmental Defects In Teeth
- Deworming Drugs For Treating Soil-transmitted Intestinal Worms In Children
- Deworming Helminth Co-infected Individuals For Delaying HIV Disease Progression
- Dexamethasone For Acute Bacterial Meningitis In Children
- Dexamethasone For The Prevention Of Altitude Sickness
- Dexamethasone Plus HT3 Receptor Antagonists Or Metoclopramide Vs Dexamethasone Alone For Chemotherapy-induced Vomiting
- Dexamethasone Vs Betamethasone For Fetal Lung Maturation For Women At Risk Of Preterm Birth
- Dexraxozane For Anthracycline Extravasation
- Dexrazoxane For Cancer Patients Receiving Anthracyclines
- Dextroamphetamine For Attention Deficit Hyperactivity Disorder In Children With Intellectual Disabilities
- Diabetes: Definition, Differential Diagnosis And Classification
- Diabetic Ketoacidosis
- Diabetic Nephropathy
- Diabetic Nephropathy - Related Resources
- Diabetic Neuropathy
- Diabetic Neuropathy - Related Resources
- Diabetic Retinopathy
- Diabetic Retinopathy: Neovascularisation And A Microinfarction - Image
- Diabetic Retinopathy During Pregancy - Image
- Diabetic Retinopathy - Related Resources
- Diabetic Retinopathy With Neovascularisation - Image
- Diacerein For Osteoarthritis
- Diagnosing Tuberculosis
- Diagnosing Tuberculosis - Related Resources
- Diagnosis, Treatment And Prevention Of Malaria In Travellers - Related Resources
- Diagnosis And Management Of Chronic Venous Disorders
- Diagnosis And Treatment Of Childhood Asthma
- Diagnosis And Treatment Of Childhood Asthma - Related Resources
- Diagnosis And Treatment Of Childhood Hypercholesterolaemia
- Diagnosis And Treatment Of Childhood Hypercholesterolaemia - Related Resources
- Diagnosis And Treatment Of Malaria
- Diagnosis Of Abdominal Aortic Aneurysm By Abdominal Palpation
- Diagnosis Of Acute Rhinosinusitis In Primary Care
- Diagnosis Of Acute Sinusitis
- Diagnosis Of Arterial Disease Of The Lower Extremities With Duplex Ultrasonography
- Diagnosis Of Diabetes Mellitus Using Glycosylated Hemoglobin Levels
- Diagnosis Of Hereditary Haemochromatosis - Image
- Diagnosis Of Hypovolemia
- Diagnosis Of Influenza On The Basis Of History And Physical Examination
- Diagnosis Of Low Back Pain In General Practice
- Diagnosis Of Otitis Media: Symptoms, Clinical Examination And Findings
- Diagnosis Of Pneumonia By History And Physical Examination
- Diagnosis Of Rib Fracture And Intercostal Nerve Block - Video
- Diagnosis Of Sinusitis - Related Resources
- Diagnosis Of Swollen Salivary Glands - Image
- Diagnosis Of Syncope
- Diagnosis Of Thyroid Diseases In Hospitalized Patients
- Diagnostic Accuracy Of Dermatoscopy In Detecting Malignant Melanoma
- Diagnostic Accuracy Of Noninvasive Fetal Rh Genotyping From Maternal Blood
- Diagnostic Accuracy Of Physical Examination In The Diagnosis Of Pleural Effusion
- Diagnostic And Prognostic Value Of Ambulatory Electrocardiographic Monitoring In Older Patients
- Diagnostic Classification Of Acute Coronary Syndromes - Image
- Diagnostic Coronary Angiography
- Diagnostic Coronary Angiography - Related Resources
- Diagnostics Of Hyponatraemia - Image
- Diagnostic Strategies For Pulmonary Embolism
- Diagnostic Tests For Carpal Tunnel Syndrome
- Diagnostic Tests For The Assessment Of Shoulder Pain
- Diagnostic Tests In Dermatology
- Diagnostic Tests In Dermatology - Related Resources
- Diagnostic Value Of Alarm Symptoms For Upper Gastrointestinal Malignancy
- Dialysis Patient In Primary Health Care
- Dialysis Patient In Primary Health Care - Related Resources
- Diaper Dermatitis Or Candida Infection - Image
- Diaphragm Versus Diaphragm With Spermicides For Contraception
- Diarrhoea And Vomiting In Children
- Diarrhoea And Vomiting In Children - Related Resources
- Diarrhoeal Diseases Caused By Microbes
- Diarrhoeal Diseases Caused By Microbes - Related Resources
- Diazepam For Treating Tetanus
- Diclofenac For Acute Migraine
- Dientamoebiasis
- Dientamoebiasis - Related Resources
- Diet And Exercise For Pregnant Women For Preventing Gestational Diabetes Mellitus
- Diet And Exercise For Weight Reduction
- Dietary Advice And Exercise For Type 2 Diabetes Mellitus
- Dietary Advice For Illness-related Malnutrition In Adults
- Dietary Advice For The Prevention Of Type 2 Diabetes Mellitus In Adults
- Dietary Advice In Pregnancy For Preventing Gestational Diabetes Mellitus
- Dietary Calcium And Blood Pressure
- Dietary Calcium Supplementation For Preventing Colorectal Cancer
- Dietary Exclusions For Established Atopic Eczema
- Dietary Fiber And Hypertension
- Dietary Fibre For The Prevention Of Colorectal Adenomas And Carcinomas
- Dietary Fibre In The Treatment Of Irritable Bowel Syndrome
- Dietary Flavonoid For Preventing Colorectal Neoplasms
- Dietary Interventions For Mineral And Bone Disorder In People With Chronic Kidney Disease
- Dietary Interventions For Rheumatoid Arthritis
- Dietary Interventions To Lower Blood Cholesterol
- Dietary Lipids And Blood Cholesterol: Metabolic Ward Studies
- Dietary Magnesium Intake Or Magnesium Supplementation And Blood Pressure
- Dietary Marine Fatty Acids (fish Oil) For Asthma In Adults And Children
- Dietary Sodium Restriction, Blood Pressure And Cardiovascular Morbidity
- Dietary Supplements For Established Atopic Eczema
- Dietary Treatment For Familial Hypercholesterolaemia
- Diet For The Prevention Of Recurrent Stones In Idiopathic Hypercalciuria
- Diethylcarbamazine (DEC)-medicated Salt For Community-based Control Of Lymphatic Filariasis
- Diethylcarbamazine Or Ivermectine For Bancroftian Filariasis
- Dieting As A Risk Factor For Eating Disorders In Children And Adolescents
- Diet Or Exercise, Or Both, For Weight Reduction In Women After Childbirth
- Diets For Obesity In Children
- Diet Therapy For High Serum Cholesterol Levels - Related Resources
- Different Anthracycline Derivates For Reducing Cardiotoxicity In Cancer Patients
- Different Antihypertensive Agents As First Line Therapies
- Different Dosage Schedules For Reducing Cardiotoxicity In Cancer Patients Receiving Anthracycline Chemotherapy
- Different Hip Prostheses In Total Hip Replacement
- Differential Diagnosis Of Broad Complex Tachycardia
- Differential Diagnosis Of Broad Complex Tachycardia - Related Resources
- Differential Diagnosis Of Mole And Melanoma
- Differential Diagnostics Of Episodic Symptoms
- Different Intensities Of Glycaemic Control For Pregnant Women With Pre-existing Diabetes
- Different Lipid Lowering Therapies In Renal Disease
- Different Models Of Palliative Care For Terminal Patients
- Different Quinolones For Uncomplicated Acute Cystitis In Women
- Different Routes Of Administration Of Non-steroidal Anti-inflammatory Drugs
- Different Types Of Dietary Advice For Women With Gestational Diabetes Mellitus
- Difficulty Breathing In A Child
- Diffuse Alopecia Areata - Image
- Diffuse Basal Cell Carcinoma On The Nose - Image
- Diffuse Interstitial Pulmonary Fibrosis (AP Projection) - Image
- Diffuse Interstitial Pulmonary Fibrosis (lateral Projection) - Image
- Diffuse Plain Xanthoma (close-up) - Image
- Diffuse Plain Xanthoma - Image
- Diffuse Scleroderma - Image
- Digitalis For Congestive Heart Failure In Patients In Sinus Rhythm
- Digoxin For Conversion To Sinus Rhythm In Atrial Fibrillation
- Dilated Cardiomyopathy
- Dilated Cardiomyopathy - Related Resources
- Dilated Sweat Glands - Image
- Dimethyl Fumarate For Multiple Sclerosis
- Dipeptidyl Peptidase-4 (DPP-4) Inhibitors For Type 2 Diabetes Mellitus
- Diphtheria
- Diphtheria - Related Resources
- Dipyridamole For Preventing Vascular Events
- Dipyridamole In Combination Of Anticoagulant Therapy In Patients With Prosthetic Heart Valves
- Dipyridamole Plus Aspirin For Stroke Prevention
- Dipyrone For Acute Renal Colic Pain
- Directly Observed Therapy (DOT) In Tuberculosis Treatment
- Direct Oral Anticoagulants
- Direct Oral Anticoagulants Versus Vitamin K Antangonists In Non-valvular Atrial Fibrillation
- Direct Oral Anticoagulants Versus Warfarin Among Atrial Fibrillation Patients With Chronic Kidney Disease
- Direct Thrombin Inhibitors Versus Vitamin K Antagonists Or LMWHs For Prevention Of Venous Thromboembolism Following Total Hip Or Knee Replacement
- Discoid Lupus Erythematosus
- Discoid Lupus Erythematosus - Image
- Discoid Lupus Erythematosus - Image (2)
- Discoid Lupus Erythematosus In The Scalp - Image
- Discoid Lupus Erythematosus On The Scalp - Image
- Discoid Lupus Erythematosus - Related Resources
- Diseases Causing Rectal Bleeding
- Diseases Of The Spinal Cord
- Disease-specific Signs And Symptoms In Patients With Inflammatory Joint Diseases
- Disease-specific Symptoms And Signs In Patients With Inflammatory Joint Diseases - Related Resources
- Dislocation Of The Acromioclavicular Joint
- Dislocation Of The Acromioclavicular Joint - Related Resources
- Dislocation Of The Elbow Joint
- Dislocation Of The Elbow Joint - Related Resources
- Dislocation Of The Patella
- Dislocation Of The Patella - Related Resources
- Dislocation Of The Shoulder
- Dislocation Of The Shoulder - Related Resources
- Dislocation Of The Temporomandibular Joint
- Dislocation Of The Temporomandibular Joint - Related Resources
- Disorders Of The Rotator Cuff Of The Shoulder
- Disorders Of The Rotator Cuff Of The Shoulder - Related Resources
- Displaced Fracture Of The Greater Tubercle Of The Humerus - Image
- Disposable Nappies For Preventing Napkin Dermatitis In Infants
- Distal - Lateral Subungual Onychomycosis - Image
- Distal Subungual Onychomycosis Caused By Trichophyton Rubrum - Image
- Distal Subungual Onychomycosis - Image
- Distal Subungual Onychomycosis - Image (2)
- Distal Subungual Onychomycosis - Image (3)
- Distal Subungual Onychomycosis In Toenails - Image
- Distal Subungual Type Of Onychomycosis - Image
- Distraction Techniques For Schizophrenia
- Distribution Of Colorectal Cancers - Image
- Disturbances Of Taste
- Disturbances Of The Sense Of Smell
- Disulfiram For Alcohol Dependence
- Disulfiram For Cocaine Dependence
- Dithranol For Chronic Plaque Psoriasis
- Diuretics As Second-line Therapy For Primary Hypertension
- Diuretics For Preventing Pre-eclampsia
- Diverticular Disease Of The Colon - Video
- Diverticulitis And Diverticulosis
- Diverticulitis And Diverticulosis - Related Resources
- Diving Medicine
- Diving Medicine - Related Resources
- Doctor's Check-ups In School Health Care - Related Resources
- Does A Toddler Or An Older Child Require Supplementation When Milk Is Eliminated From The Diet?
- Does The Efficacy Of BCG Vaccine Decline With Time?
- Does This Patient With Headache Need Neuroimaging?
- Domiciliary Oxygen For Interstitial Lung Disease
- Domiciliary Oxygen In Chronic Obstructive Pulmonary Disease
- Dominant Ovarian Follicle (ultrasound Scan) - Image
- Donepezil For Alzheimer's Disease
- Donepezil For Mild Cognitive Impairment
- Donepezil For Vascular Cognitive Impairment
- Dopamine Agonists For Cocaine Dependence
- Dopamine Agonists For Preventing Ovarian Hyperstimulation Syndrome
- Dopamine Agonists For The Treatment Of Restless Legs Syndrome
- Dopamine Agonist Therapy In Early Parkinson's Disease
- Dopaminergic Agonists For Hepatic Encephalopathy
- Doppler Stethoscope In The Diagnosis Of Testicular Torsion
- Doppler Stethoscopy In Diagnostics
- Doppler Ultrasound For Foetal Assessment In High Risk Pregnancies
- Doppler Ultrasound In The Diagnosis Of Deep Venous Thrombosis
- Dornase Alfa For Cystic Fibrosis
- Dorsal Tenosynovitis Of The Wrist In A Patient With Rheumatoid Arthritis - Video
- Dose-related Mortality In Patients With Coronary Heart Disease Using Nifedipine
- Dose-response Characteristics Of Cholesterol-lowering Drug Therapies
- Dose-response Effect Of Aspirin On Stroke
- Doses Needed To Elicit Reaction During Food Challenge
- Double Gloving To Reduce Surgical Cross-infection
- Down's Syndrome
- Down's Syndrome - Related Resources
- Doxycycline For Osteoarthritis Of The Knee Or Hip
- Doxycycline For Uncomplicated Genital Chlamydial Infection
- D-penicillamine For Primary Biliary Cirrhosis
- Drainage Of A Peritonsillar Abscess
- Drainage Of A Peritonsillar Abscess - Related Resources
- Dressings And Topical Agents For Arterial Leg Ulcers
- Dressings And Topical Agents For Preventing Pressure Ulcers
- Dressings And Topical Agents For Treating Pressure Ulcers
- Dressings For Superficial And Partial Thickness Burns
- Dronedarone For Maintaining Sinus Rhythm After Cardioversion Of Atrial Fibrillation
- Dronedarone In Atrial Fibrillation
- Dronedarone In The Prevention Of Atrial Fibrillation - Image
- Droperidol For Psychosis-induced Aggression Or Agitation
- Drop-shaped Optic Nerve Cup In Open-angle Glaucoma - Image
- Drotrecogin Alfa For Severe Sepsis In Adults
- Drug Abuse Treatment As An HIV Prevention Strategy
- Drug Exanthema - Image
- Drug-induced Thrombocytopenia
- Drug Interactions With Azole Antifungal Agents
- Drug Management For Acute Tonic-clonic Convulsions In Children
- Drug Poisoning
- Drug Poisoning - Related Resources
- Drugs For Chronic Heart Failure With Preserved Ejection Fraction
- Drugs For Discoid Lupus Erythematosus
- Drugs For Intraoperative And Postoperative Nausea And Vomiting
- Drugs For Malaria In Pregnant Women
- Drugs For Preventing Malaria-related Illness In Pregnant Women And Death In The Newborn
- Drugs For Preventing Tuberculosis In HIV Infected Persons
- Drugs For Rapid Treatment Of Very High Blood Pressure During Pregnancy
- Drugs For The Acute Treatment Of Migraine In Children And Adolescents
- Drugs For The Treatment Of Dysthymia
- Drugs For Treating Giardiasis
- Drugs For Treating Schistosoma Mansoni-infection
- Drugs For Treatment Of Urinary Retention After Surgery In Adults
- Drugs For Ventricular Rate Control In Atrial Fibrillation
- Drugs Improving Insulin Resistance For Non-alcoholic Fatty Liver Disease And/or Non-alcoholic Steatohepatitis
- Drugs Used In Alcohol Dependence
- Drugs Used In Alcohol Dependence - Related Resources
- Drugs Used In Psychiatric Emergencies
- Drugs Used In Psychiatric Emergencies - Related Resources
- Drug Therapies For Reducing Gastric Acidity In People With Cystic Fibrosis
- Drug Therapy For Preventing Post-dural Puncture Headache
- Drug Therapy For The Management Of Cancer Related Fatigue (CRF)
- Drug Therapy For Treating Post-dural Puncture Headache
- Drug Treatment For ADHD In Children With Comorbid Tic Disorders
- Drug Treatment For Faecal Incontinence In Adults
- Drug Treatment For Hypertension
- Drug Treatment For Hypertension - Related Resources
- Drug Treatment For Myotonia
- Drug Treatments For Lice
- Drug Treatments For Obstructive Sleep Apnoea
- Drusens In A Patient With Nonexudative Macular Degeneration - Image
- Dry Eye Syndrome
- Dryness Of The Mouth
- Dryness Of The Mouth - Related Resources
- Dual Alpha And Beta Blockers For Primary Hypertension
- Dual Diagnosis (mental Illness And Substance Abuse)
- Dual Diagnosis (mental Illness And Substance Abuse) - Related Resources
- Ductal Breast Cancer In Mammography - Image
- Ductus Arteriosus - Audio
- Ductus Arteriosus - Image
- Ductus Arteriosus In A 2.6-year-old - Audio
- Ductus Arteriosus In A 2.6-year-old - Image
- Ductus Arteriosus In A Newborn - Audio
- Ductus Arteriosus In A Newborn - Image
- Duloxetine For Fibromyalgia In Adults
- Duloxetine For Treating Painful Neuropathy, Chronic Pain Or Fibromyalgia
- Duloxetine Versus Other Anti-depressive Agents For Depression
- Dupuytren's Contracture
- Dupuytren's Contracture - Image
- Dupuytren's Contracture - Related Resources
- Duration And Intensity Of Maintenance Chemotherapy In Acute Lymphoblastic Leukaemia In Children
- Duration Of Adjuvant Chemotherapy For Patients With Non-metastatic Colorectal Cancer
- Duration Of Antibacterial Treatment For Uncomplicated Urinary Tract Infection In Women
- Duration Of Antibacterial Treatment For Uncomplicated Urinary Tract Infection In Women (2)
- Duration Of Antibiotic Therapy For Ventilator-associated Pneumonia In Critically Ill Adults
- Duration Of Antibiotic Treatment In Asymptomatic Bacteriuria In Pregnancy
- Duration Of Anticoagulant Therapy In Venous Thromboembolism
- Duration Of Breastfeeding As Risk Factor For Acute Otitis Media
- Duration Of Prophylaxis Against Venous Thromboembolism After Surgery For Cancer
- Dynamic Exercise Therapy For Rheumatoid Arthritis
- Dyshidrotic Eczema (pompholyx) In The Hand - Image
- Dysmenorrhoea
- Dysmenorrhoea - Related Resources
- Dyspareunia In Women
- Dyspareunia In Women - Related Resources
- Dyspepsia
- Dyspepsia - Related Resources
- Dysphagia And Globus Sensation (globus Pharyngeus)
- Dysphagia And Globus Sensation (globus Pharyngeus) - Related Resources
- Dyspnea At Cardiac Stress Testing As Predictor Of Death
- Dyspnoea
- Dystrophic Nail In A Patient With Chronic Hand Eczema - Image
Evidence-Based Medicine Guidelines